Doppler Laser Imaging Predicts Response to Topical Minoxidil in the Treatment of Female Pattern Hair Loss

    July 2016 in “ PubMed
    Francesco Traina, Fabrizio Perna, Alberto Ruffilli, Antonio Mazzotti, Riccardo Meliconi, Lisa Berti, Cesare Faldini
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    Studysummary This study found that laser Doppler velocimetry can non-invasively predict topical minoxidil response by correlating scalp blood flow changes with sulfotransferase enzyme activity in women with pattern hair loss.
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    The study demonstrated that laser Doppler imaging could predict the response to topical minoxidil in treating female pattern hair loss. Researchers found a strong correlation (r=1.0) between scalp blood perfusion changes within 60 minutes of minoxidil application and sulfotransferase enzyme activity in plucked hair follicles. This suggested that laser Doppler imaging could serve as a rapid, non-invasive diagnostic test to predict minoxidil response, potentially improving treatment outcomes for patients.
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