Moth-Eaten Essential Syphilitic Alopecia

    July 2014 in “ QJM
    Hua‐Li Cao, Michelle Yixiao Engle, Yulong Shen, Jianyou Wang
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    TLDR A 35-year-old man had patchy hair loss that was actually due to syphilis, not alopecia areata.
    A 35-year-old man experienced progressive patchy hair loss over 5 months, initially diagnosed as alopecia areata and treated unsuccessfully with minoxidil. Despite no recent sexual activity or history of genital or mouth ulceration, physical examination revealed diffuse non-scarring, ‘moth-eaten’ patches of alopecia across his scalp.
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      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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      Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

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      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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