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Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Some breast cancer chemotherapy can cause permanent hair loss.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.