research The Mineralocorticoid Receptor as a Novel Player in Skin Biology: Beyond the Renal Horizon?
The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
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research Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats
Finasteride helps reduce blood vessel growth in diabetic rat kidneys.
research Hormonal Manipulation with Finasteride or Oral Contraception Does Not Influence Incidence of Renal Cell Carcinoma
research Oxalate Nephropathy Secondary to Enteric Hyperoxaluria: A Rare Cause of End Stage Renal Failure – A Report of 2 Cases
Enteric hyperoxaluria can cause severe kidney failure after bowel surgery.
research Growth Hormone Deficiency with Late-Onset Hypothalamic Hypoadrenocorticism Associated with Respiratory and Renal Dysfunction: A Case Report
A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.
research Comparative Study of Cutaneous Manifestations in Patients with Chronic Kidney Disease, Patients on Hemodialysis, and Renal Transplant Recipients
Skin problems are common in kidney disease, with dry skin and itching in patients not on dialysis or on hemodialysis, and infections most common in transplant recipients.
research Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota
Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.
research Deletion of DNA Binding Domain of the Vitamin D Receptor Abrogates Genomic and Nongenomic Functions of Vitamin D
Removing part of the vitamin D receptor stops vitamin D from working properly.
research Long-Term Sequelae of Drug Reaction with Eosinophilia and Systemic Symptoms: A Retrospective Cohort Study from Taiwan
Young patients are more likely to develop autoimmune diseases, while elderly patients are more prone to organ failure after DRESS.
research The Pharmacology of Methotrexate
Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.
research Flares of Systemic Lupus Erythematosus During Pregnancy and the Puerperium: Prevention, Diagnosis, and Management
Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
research FLCN, A Novel Autophagy Component, Interacts With GABARAP And Is Regulated By ULK1 Phosphorylation
The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
research Molecular Targeted Therapies for Cancer: Sorafenib Monotherapy and Its Combination with Other Therapies
Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.
research Comedonal and Cystic Fibrofolliculomas in Birt-Hogg-Dube Syndrome
Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.
research Trichoscopic Signs in Systemic Lupus Erythematosus: A Comparative Study with 109 Patients and 305 Healthy Controls
Trichoscopy is useful for diagnosing and monitoring systemic lupus erythematosus, with certain hair and scalp changes indicating more active disease.
research Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.
research Skin Manifestations of Chronic Kidney Disease
Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.
research Acute and 30-Day Oral Toxicity Studies of a Novel Coccidiostat – Ethanamizuril
Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
research Trichodysplasia Spinulosa: Rare Presentation of Polyomavirus Infection in Immunocompromised Patients
Antiviral medication valganciclovir may improve skin and hair in Trichodysplasia Spinulosa patients.
research Pediatric Systemic Lupus Erythematosus
Early and aggressive treatment with individualized care plans is crucial for managing pediatric systemic lupus erythematosus.
research Viremia and Viruria of Trichodysplasia Spinulosa-Associated Polyomavirus Before the Development of Clinical Disease in a Kidney Transplant Recipient
The virus linked to a rare disease was found in a patient's blood and urine before skin symptoms appeared.
research Birt-Hogg-Dubé Syndrome: Genetic and Clinical Insights
Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.
research The Hydroxypropyl-β-Cyclodextrin-Minoxidil Inclusion Complex Improves the Cardiovascular and Proliferative Adverse Effects of Minoxidil in Male Rats: Implications in the Treatment of Alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research Relation of Urinary Stone Disease with Androgenetic Alopecia and Serum Testosterone Levels
Balding and low testosterone increase risk of urinary stones.
research Chronic Tophaceous Gout Secondary to Self-Induced Vomiting in Anorexia Nervosa
A woman with anorexia developed gout from self-induced vomiting.
research Paraphenylenediamine Hair Dyeing Nephropathy: A Case Report and Review of Literature
Hair dye chemicals can cause serious health problems, including kidney damage.
research Unusual Acute Lupus Hemophagocytic Syndrome – A Test of Diagnostic Criteria: A Case Report
The 2012 criteria are better for diagnosing atypical lupus cases.
research Skin Manifestations of Bardet-Biedl Syndrome
Bardet-Biedl syndrome may include under-recognized skin problems related to its metabolic disturbances.
research Immunohistochemical, Pharmacovigilance, and Omics Analyses Reveal the Involvement of ATP-Sensitive K+ Channel Subunits in Cancers: Role in Drug-Disease Interactions
ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
research Mycophenolate Mofetil in Induction and Maintenance Therapy for Juvenile Onset Severe Lupus Nephritis
Mycophenolate mofetil is effective for treating severe lupus nephritis in children.