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The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.

This study suggests that lipin-1 plays a crucial role in keratinocyte differentiation by modulating protein kinase C activity through diacylglycerol levels, with implications for skin biology.

This study found that the ethanolic extract of walnut fruit diaphragm significantly improved lipid profiles, reduced oxidative stress, and had anti-inflammatory effects in hyperlipidemic rats.

This study found that weanling rats fed diets with oxidized rapeseed oil or lard had increased heart lipid levels, various symptoms of fat toxicity, and organ-specific tissue damage.

Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.

This study investigated lipid loss in hair caused by surfactants and found that surface and internal modifications can significantly protect different lipids from depletion, with internal modification preventing 52.0 to 81.3% of lipids in certain groups.

This study reviews progress in understanding how redesigned lipid metabolism supports energy production and treatment resistance in advanced carcinomas, highlighting a hypothesis supported by preclinical and clinical evidence and suggesting potential clinical targeting of resistance mechanisms.

In this study, researchers found that the cell surface protein Lrig1 plays a crucial role in regulating the suppressive function of regulatory T cells, suggesting it as a potential target for treating autoimmune diseases, as evidenced by experiments in mouse models.

This study found that high doses of cloforex and chlorphentermine caused pulmonary lipid histiocytosis and toxic effects in rats, but did not induce pulmonary hypertension.

This review summarizes recent discoveries of GPCRs for lysophosphatidylserine and lysophosphatidylinositol, detailing their roles as lipid mediators, but reports no new experimental results.

This study found that oral tetracycline hydrochloride significantly reduced the free fatty acid/triglyceride ratio in hair lipids of young men and women treating acne vulgaris, with or without additional ethyl lactate application.

Repaglinide-loaded liponiosomal hybrids improve blood sugar control and insulin release better than regular Repaglinide.

This study found that the rs1128977 SNP in the RXRG gene may be linked to altered clinical characteristics such as higher HDL-cholesterol levels and increased body mass index in individuals with dyslipidemia.

This review highlights the limited research on sebocyte lipid droplets and their proteins despite their role in sebocyte differentiation and potential involvement in skin diseases like acne and alopecia, and reports no new results.

This case report presents a patient with necrobiosis lipoidica exhibiting transepithelial elimination of cholesterol crystals through hair follicles, a finding previously associated with necrobiotic xanthogranuloma.

This study found that chemical lumbar sympathectomy with 5% phenol effectively treated idiopathic livedo reticularis in most patients, offering a potential long-lasting solution with repeatable efficacy upon recurrence.

This study found that lipid and acne inhibitive cream improved the skin condition in a rabbit ear acne model, showing significant changes in follicular cornification.

This study found that impaired TCF/Lef1 signaling in mice leads to significant skin barrier defects due to altered lipid metabolism and epidermal differentiation.

This review discusses insights into the role of lipase H in controlling hair form and texture, emphasizing genetic mutations linked to autosomal recessive woolly hair/hypotrichosis, and reports no new experimental results.

In this study, the use of internal wool lipid liposomes was shown to improve the lipid composition and increase the resistance to breaking in both untreated and chemically treated hair fibers.

This study found that paeonol-loaded liposomal gels demonstrated antioxidant effects and relieved inflammation in AD-like mice, suggesting potential benefits for treating atopic dermatitis.

In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.

This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.

This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.

This review discusses the etiology, clinical features, and treatment options for lipedema and lipedematous scalp and reports no new clinical results.

Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.

This study identified compound heterozygous mutations, c.1101del and c.736 T > A, in the LIPH gene responsible for causing autosomal recessive woolly hair in a child, with c.1101del being a novel frameshift mutation.

This study found that the aromatic retinoic acid derivative Ro 10-9359 provided excellent results in 64% of severe psoriasis patients, especially in those with erythrodermic and pustular types, though relapses and side effects were noted.

This report presents two cases of Berardinelli–Seip syndrome, emphasizing the role of genetic analysis and comprehensive care in managing the variability and complications of this rare condition.

Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.