Oral Treatment of Severe Psoriasis With a New Aromatic Retinoid (Ro 10-9359)

The user is seeking a substitute for Tretinoin to enhance the effectiveness of Minoxidil for hair loss. They are considering using Retinol as an alternative.

Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

Tazarotene may be more effective than tretinoin when combined with topical minoxidil for hair loss due to its selective binding to RAR-beta and gamma, though it can cause irritation. Tazarotene's potency can lead to indirect inflammatory reactions despite potentially causing less irritation than tretinoin.

User is using minoxidil with tretinoin 0.025% and experiencing peeling and burning on the scalp. They are unsure if it's effective or if they are using it too frequently.

The conversation discusses using 0.1% retinol as a potential substitute for 0.01% tretinoin with minoxidil for hair loss treatment. It mentions that tretinoin is not easily available in some countries, and retinol might be less effective but less harsh on the scalp.

Minoxidil may cause dark circles and affect collagen, and Tretinoin might help counteract these effects. Users suggest caution with Tretinoin due to potential Vitamin A toxicity and recommend using it sparingly with sunscreen and moisturizer.