19 citations
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June 2007 in “Veterinary Dermatology” In this study, amitraz was found to be an effective and well-tolerated treatment for resolving sarcoptic mange in alpacas, demonstrating no relapse over a 10-month follow-up.
18 citations
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August 2011 in “Clinical Drug Investigation” This study found that a combination of low-dose isotretinoin and oral azithromycin pulse effectively treats severe acne with an acceptable side effect profile and relatively low relapse rates.
16 citations
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December 2015 in “Journal of Investigative Dermatology” This study found significant gene expression abnormalities in hair follicles affected by alopecia areata, suggesting persistent changes that may predispose to future relapses even after hair regrowth.
16 citations
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April 2014 in “Expert Opinion on Pharmacotherapy” This review discusses the pharmacological profile of teriflunomide for treating relapsing multiple sclerosis, highlighting its safety and effectiveness in reducing relapses and slowing disability progression, though direct comparisons with other oral medications are lacking.
12 citations
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April 2005 in “Mycoses” This study found that 1-day itraconazole therapy was more effective for acute vulvovaginal candidosis than for recurrent cases, where relapses occurred despite no yeast resistance.
12 citations
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October 1978 in “PubMed” This study found that the aromatic retinoic acid derivative Ro 10-9359 provided excellent results in 64% of severe psoriasis patients, especially in those with erythrodermic and pustular types, though relapses and side effects were noted.
11 citations
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February 2021 in “Journal of Cosmetic Dermatology” This retrospective pilot study found that oral tofacitinib was more effective in treating alopecia areata than alopecia universalis, but relapses were common after treatment cessation.
9 citations
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August 2024 in “Cureus” This study reviewed existing knowledge and research, observing that ketoconazole shampoo is a safe and effective treatment for scalp seborrheic dermatitis, significantly improving irritation and scaling while maintaining low relapse rates and minimal side effects.
9 citations
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January 2004 in “Journal of dermatological treatment” This study reports that oral rifampicin effectively treated the pustular lesions of tufted hair folliculitis in a 47-year-old woman, with no relapses after one year.
1 citations
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February 2023 in “Deleted Journal” This study found that Diphenylcyclopropenone (DCP) was effective for treating extensive alopecia areata in Thai patients, although a high relapse rate suggests maintenance therapy might be necessary.
1 citations
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October 2010 in “Faṣlnāmah-i bīmārīhā-yi pūst” This study found that using methotrexate with corticosteroids may support hair regrowth in severe alopecia areata, but adverse effects and relapses were common, suggesting more controlled trials are needed.
June 2026 in “Pediatric Drugs” This study analyzed systemic treatment patterns in 262 French children with severe alopecia areata, finding that while intravenous corticosteroids were most commonly used initially, treatment effectiveness appeared limited with frequent relapses and a need for prolonged therapy, but without serious adverse events.
May 2026 in “International Journal For Multidisciplinary Research” This abstract highlights that while treatments for alopecia areata, like corticosteroids and JAK inhibitors, exist, their effectiveness varies and relapses are common, prompting interest in supplementary therapies.
May 2026 in “International Journal of Homoeopathic Sciences” This study found that individualized homeopathic medicine can significantly improve outcomes in patients with alopecia areata, including complete hair regrowth and reduced SALT scores within 5 to 12 months, without relapse, and shows promise for alopecia universalis through targeted miasmatic and constitutional remedies.
April 2026 in “Boletín Médico Del Hospital Infantil de México (English Edition)” This study found that 90% of pediatric patients with alopecia areata had comorbidities, including allergic rhinitis and atopic dermatitis, with localized AA being associated with better treatment outcomes and fewer relapses compared to non-localized forms.
March 2026 in “Immunological Medicine” This review discusses the use of Janus kinase inhibitors for severe alopecia areata in Japan, noting their effectiveness in some patients but highlighting the need for new therapies due to non-responsiveness and relapse in others; it reports no new clinical results.
January 2026 in “Dermatology and Venerology” This study at the Dzerkalo Medical Center found that complex therapy for abscessing perifolliculitis of the scalp is more effective in reducing inflammation and follicle destruction compared to basic antibacterial therapy, which was associated with relapses during long-term follow-up.
September 2025 in “International Journal of Innovative Technologies in Social Science” This review highlights that while pharmacotherapy, including biological agents, provides varying but often partial control of hidradenitis suppurativa depending on disease severity, significant challenges and high relapse rates persist, necessitating further research for more effective treatments.
August 2025 in “Veterinary Dermatology” This study examined 14 dogs with alopecia areata and found that oral ciclosporin was the most common treatment, with some dogs experiencing hair regrowth, though relapses were common when the medication was tapered or withdrawn.
July 2025 in “International Journal of Homoeopathic Sciences” This case study from Dr. Batra’s discusses how individualized homeopathic management guided by miasmatic understanding may offer long-term relief for a young male patient with alopecia areata and recurrent urticaria, suggesting an alternative to conventional treatments that often result in relapses and side effects.
June 2025 in “Journal of Education Health and Sport” This review discusses the role of JAK inhibitors in treating alopecia areata by targeting the JAK/STAT pathway and highlights the promising results but also ongoing challenges such as relapse risk and side effects.
This study of patients with moderate to severe alopecia areata in Morocco found that oral betamethasone mini-pulses yielded ≥50% hair regrowth in 62.5% of cases, improved quality of life scores, and were generally well-tolerated, though relapses and mild side effects were noted.
This case report describes a 28-year-old woman who developed alopecia areata following prolonged emotional stress, with improvement observed using Minoxidil and stress management, but relapse occurred after another stressful period.
January 2025 in “Вопросы современной педиатрии” This study discusses the role of Janus kinase inhibitors in treating severe alopecia areata, highlighting their potential to personalize treatment and improve patient quality of life, while addressing concerns about disease relapse after stopping treatment and the safety of long-term use.
April 2024 in “Expert opinion on investigational drugs” In this study, JAK inhibitors were reported as safe and effective treatments for moderate-to-severe chronic alopecia areata, although the appropriate duration of treatment remains uncertain, as stopping these medications often results in relapse.
January 2024 in “Wiadomości Lekarskie” This paper reviews the development and implementation of CAR-T cell therapy as a significant advancement in treating pediatric hematological malignancies, particularly for children with relapsed or chemotherapy-resistant acute lymphoblastic leukemia, offering renewed remission prospects where conventional methods are ineffective.
June 2023 in “Dermatology and Therapy” This study found that for patients with moderate-to-severe chronic hand eczema, combining fractional CO2 laser with halometasone cream was more effective than using halometasone cream alone, with a higher treatment success rate and fewer relapses, though skin pigmentation was a common side effect.
September 2021 in “Pediatrics in review” This case report describes a 2-year-old girl with Majocchi granuloma, a deep granulomatous folliculitis, which improved after treatment with oral terbinafine despite relapses leading to multiple treatment courses.
January 2021 in “International journal of basic and clinical pharmacology” This study found that hydroxychloroquine was less effective than betamethasone oral mini pulse therapy in managing alopecia areata, with patients on hydroxychloroquine experiencing score increases and more relapses at 24 weeks, though adverse event rates were similar between the groups.
This case series reports favorable outcomes for children with Parry Romberg Syndrome who underwent facial fat-grafting, showing it as a safe and well-tolerated procedure with no complications or relapses observed.