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    Modern Management Approaches for Alopecia Areata

    Eduard Т. Ambarchian, Vladislav V. Ivanchikov, Anastasia D. Kuzminova … Leyla S. Namazova-Baranova
    Studysummary This study discusses the role of Janus kinase inhibitors in treating severe alopecia areata, highlighting their potential to personalize treatment and improve patient quality of life, while addressing concerns about disease relapse after stopping treatment and the safety of long-term use.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 42

    1. Disease Burden, Clinical Management, and Unmet Treatment Need of Patients With Moderate to Severe Alopecia Areata: Consensus Statements, Insights, and Practices From CERTAAE Delphi Panel Frontiers in medicine · 2024
    2. TNF-α Inhibitor-Induced Psoriasis and Psoriatic Alopecia in an Adolescent with Ulcerative Colitis: Clinical Case Вопросы современной педиатрии · 2023
    3. Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions Frontiers in immunology · 2023
    4. Successful Treatment of Alopecia Universalis With Abrocitinib: A Case Report Journal of Dermatological Treatment · 2023
    5. Efficacy and Safety of Ritlecitinib in Adolescents with Alopecia Areata: Results from the ALLEGRO Phase 2b/3 Randomized, Double-Blind, Placebo-Controlled Trial Pediatric Dermatology · 2023
    6. Alopecia Areata: An Updated Review for 2023 Journal of Cutaneous Medicine and Surgery · 2023
    7. Adverse Events in Patients Treated With Jak-Inhibitors for Alopecia Areata: A Systematic Review JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2023
    8. Efficacy and Safety of Baricitinib in Patients with Severe Alopecia Areata Over 52 Weeks in Phase III Trials American Journal of Clinical Dermatology · 2023
    9. Ideal JAK Inhibitor for Alopecia Areata: Baricitinib, Tofacitinib, Ritlecitinib, or Ifidancitinib - Revisiting the Immunomechanisms of the JAK Pathway Indian Dermatology Online Journal · 2023
    10. Trichoscopy in Alopecia Areata Actas Dermo-Sifiliográficas · 2022
    11. The National Pediatric Alopecia Areata Registry in Russia: An Overview Journal of the American Academy of Dermatology · 2022
    12. A Case of Atopic Dermatitis with Alopecia Universalis in a Patient Treated with Abrocitinib JAAD case reports · 2022
    13. Evaluating the Therapeutic Potential of Ritlecitinib for the Treatment of Alopecia Areata Drug Design Development and Therapy · 2022
    14. The JAK/STAT Signaling Pathway: From Bench to Clinic Signal Transduction and Targeted Therapy · 2021
    15. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    16. Alopecia Areata: An Autoimmune Disease of Multiple Players ImmunoTargets and therapy · 2021
    17. A Comprehensive Literature Review of JAK Inhibitors in the Treatment of Alopecia Areata Clinical, cosmetic and investigational dermatology · 2021
    18. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    19. Italian Guidelines in Diagnosis and Treatment of Alopecia Areata Giornale italiano di dermatologia e venereologia · 2019
    20. Frontiers in Alopecia Areata Pathobiology Research ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology · 2019
    21. Targeting the Janus Kinase Family in Autoimmune Skin Diseases Frontiers in Immunology · 2019
    22. What Is Behind the 'Swarm of Bees' in Alopecia Areata British Journal of Dermatology · 2018
    23. JAK Inhibitors for Treatment of Alopecia Areata ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2018
    24. An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis Journal of Investigative Dermatology · 2018
    25. Nail Changes in Alopecia Areata: An Update and Review International Journal of Dermatology · 2018
    26. Tofacitinib for the Treatment of Severe Alopecia Areata in Adults and Adolescents Journal of Investigative Dermatology Symposium Proceedings · 2017
    27. Brazilian Experience of Treating Alopecia Universalis with Novel Antirheumatic Therapy Tofacitinib: A Case Series Rheumatology and Therapy · 2017
    28. Topical Janus Kinase Inhibitors for the Treatment of Pediatric Alopecia Areata Journal of the American Academy of Dermatology · 2017
    29. High-Dose Pulsed Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata in Childhood JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2017
    30. JAK Inhibitors in Dermatology: The Promise of a New Drug Class Journal of the American Academy of Dermatology · 2017
    31. Hair Pull Test: Evidence-Based Update and Revision of Guidelines Journal of The American Academy of Dermatology · 2016
    32. Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata JCI insight · 2016
    33. Efficacy and Safety of Methotrexate Combined with Low- to Moderate-Dose Corticosteroids for Severe Alopecia Areata Dermatology · 2016
    34. The Role of Lymphocytes in the Development and Treatment of Alopecia Areata Expert Review of Clinical Immunology · 2015
    35. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    36. Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis Journal of Investigative Dermatology · 2014
    37. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013
    38. Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata Clinical and Developmental Immunology · 2013
    39. Interest of High-Dose Pulse Corticosteroid Therapy Combined with Methotrexate for Severe Alopecia Areata: A Retrospective Case Series Dermatology · 2012
    40. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    41. The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians International Journal of Dermatology · 2002
    42. Profile of Alopecia Areata: A Questionnaire Analysis of Patients and Families International Journal of Dermatology · 1992

    Related research 4

    1. Alopecia Areata: A Multifactorial Autoimmune Condition Journal of autoimmunity · 2018
    2. Linear Alopecia Areata JAAD case reports · 2018
    3. Treating Resistant Cases of Alopecia Universalis Journal of cosmetology & trichology · 2018
    4. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013