research New Frontiers in CRISPR/Cas9 Delivery Systems for Gene Editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
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90-120 / 865 results research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair
TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research The Multiple Consequences Of Obesity
Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.
research Melanocytes in Regenerative Medicine Applications and Disease Modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Nanotechnology-Based Techniques for Hair Follicle Regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research Mineral Deficiencies: A Root Cause for Reduced Longevity in Mammals
Not getting enough minerals can lead to health problems and shorter lifespans.
research Long-Term Differential Changes in Mouse Intestinal Metabolomics After Gamma and Heavy Ion Radiation Exposure
Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Mechanisms of Repigmentation Induced by Photobiomodulation Therapy in Vitiligo
Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.
research Identification of Hepatic Molecular Mechanisms of Action of Alpha-Tocopherol Using Global Gene Expression Profile Analysis in Rats
Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth
Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
research A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research The Coenzyme A Precursor Pantethine Enhances Antitumor Immunity in Sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research Signaling Pathways in Hair Aging
Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
research Nocturnal Eczema: Review of Sleep and Circadian Rhythms in Children with Atopic Dermatitis and Future Research Directions
Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Effect of Ultraviolet Radiation, Smoking, and Nutrition on Hair
Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
research Hair Growth Promoting Effect of Houttuynia Cordata Extract in Cultured Human Hair Follicle Dermal Papilla Cells
Houttuynia cordata extract may help hair grow by improving cell survival and increasing cell growth.
research Illuminating Microflora: Shedding Light on the Potential of Blue Light to Modulate the Cutaneous Microbiome
Blue light might help treat skin conditions by affecting the skin's bacteria.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
Hair color is determined by melanin produced and transferred in hair follicles.
research Immunological and Metabolic Causes of Infertility in Polycystic Ovary Syndrome
PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.