62 citations
,
January 2000 in “Developmental dynamics” This study found that Notch-related genes, including Notch1 and Notch2, and their ligands and regulators, have distinct patterns of expression during mouse hair vibrissa follicle development and the adult hair cycle.
54 citations
,
August 2009 in “Dermatologic Surgery” This review outlines the steps of contemporary hair transplantation surgery, including the roles of medications and nonsurgical options, but it reports no new clinical findings.
46 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses techniques for creating natural-looking hairlines in hair restoration surgery and reports no new clinical results.
45 citations
,
May 2003 in “Journal of Cell Science” This study found that α3β1-integrin is crucial for maintaining normal hair follicle morphology in mice, as its deficiency leads to severe abnormalities despite not affecting interfollicular epidermal differentiation.
40 citations
,
December 1980 in “The Journal of Dermatologic Surgery and Oncology” This review describes an improved scalp reduction technique that removes two to three times more bald skin than previous methods, utilizing wide undermining, serial relaxing incisions, and adrenocorticosteroids.
36 citations
,
October 1996 in “Dermatologic Clinics” In this study, a methanol extract of Eclipta alba was found to have dose-dependent hair growth-promoting activity in C57BL6 mice.
33 citations
,
December 2004 in “Differentiation” In this study, mouse amnion epithelium was successfully transformed into skin and hair follicles when associated with hair-forming dermis, revealing the necessity of specific influences for follicle formation.
32 citations
,
September 1997 in “Dermatologic Surgery” This study found that mini-micrografting and plug methods achieve comparable hair density, but mini-micrografting requires fewer sessions due to its dense graft packing.
31 citations
,
October 2017 in “Dermatologic Surgery” This review examines controversies in hair transplant surgery, including donor harvesting techniques and the roles of platelet-rich plasma and low-level light therapy, and reports no new clinical results.
31 citations
,
March 2011 in “Dermatologic Surgery” This study classified hairline contours in Asian women and concluded that their refined hair transplantation techniques may help correct wide foreheads with M-shaped or rectangular hairline contours.
31 citations
,
October 2002 in “Dermatologic Surgery” This article reviews expert opinions on combining pharmacologic treatments like minoxidil with hair transplantation, reporting improved hair density and regrowth in patients with partially functioning follicles.
30 citations
,
December 2018 in “Trends in Endocrinology and Metabolism” The authors concluded that dermal white adipose tissue, influenced by factors like light irradiation, plays a significant role in modulating hair follicle cycles and could be targeted for hair growth treatments.
30 citations
,
March 2017 in “ACS biomaterials science & engineering” This review discusses the structure and regenerative potential of hair follicles, highlighting their role in wound healing, stem cell populations, and keratin-based biomaterials, but it reports no new clinical results.
30 citations
,
October 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This article reviews modern hair transplantation techniques, noting that while many innovations have improved natural-looking results and expanded candidate eligibility, some may have hidden drawbacks, and it reports no new results.
27 citations
,
June 2023 in “Nature” In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
26 citations
,
March 2013 in “Journal of Biomedical Materials Research Part A” This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.
25 citations
,
May 2011 in “Annals of Plastic Surgery” This study reported that follicular unit extraction using nonhead hair sources like the chest or beard may successfully restore hair density and achieve aesthetically pleasing results in severely bald men with limited head donor hair.
25 citations
,
November 2008 in “Facial Plastic Surgery” This article explores factors in designing a personalized hairline, favoring a flared design approach, and reports no new evidence.
23 citations
,
September 2014 in “Journal of The American Academy of Dermatology” This study reports that a robotic device effectively harvests hair follicles with a 95.1% yield in Korean patients undergoing hair restoration surgery.
22 citations
,
December 1998 in “Dermatologic Surgery” This study found that preserving hair micrografts in an enriched storage medium for five hours significantly increased their survival rate compared to those stored in saline.
21 citations
,
December 2013 in “Archives of Dermatological Research” No link found between new male baldness genes and female hair loss.
21 citations
,
October 2009 in “Biochemical Engineering Journal” This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.
20 citations
,
January 2015 in “Current problems in dermatology” This paper reviews recent research on hair graying, suggesting that an imbalance in oxidative stress handling may affect melanocyte stem cells and melanin production with age, and calls for exploring strategies to prolong melanin production.
20 citations
,
May 1992 in “The Journal of Dermatologic Surgery and Oncology” This article discusses patient selection and procedural design for hair transplant surgery without reporting new clinical results; it also considers how hair transplant designs can align with various hairstyles.
19 citations
,
August 2011 in “Facial Plastic Surgery Clinics of North America” This article discusses the use of hair transplantation as a reconstructive method to restore hair in various areas affected by defects, highlighting its advantages in providing natural-looking restoration.
18 citations
,
August 2018 in “The FASEB journal” This study found that Hoxc13-/- rabbits exhibit complete hair loss on the head and dorsum, providing a potential model for understanding human ECTD-9 and related dermatological conditions.
17 citations
,
May 2015 in “Aesthetic Plastic Surgery” FUE hair transplantation using a micromotor is effective and gives natural results with few complications.
17 citations
,
October 2002 in “Dermatologic Surgery” This article provides a guide for surgeons on repairing poorly executed hair transplants, emphasizing meticulous techniques and optimal use of limited hair supply to achieve cosmetic improvements.
16 citations
,
December 2019 in “Animals” In this study, cashmere goats engineered to overexpress the Tβ4 gene in hair follicles produced more cashmere, indicating that Tβ4 promotes secondary hair follicle development and enhances yield.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article describes a technique for improving the aesthetic results of surgical hair restoration by recycling plug grafts into smaller grafts, which can be combined with other procedures like scalp lifting and reductions.