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Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride lowers good cholesterol, raises bad fats, and may increase heart disease risk.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Lipase H is important for hair follicle function and shaping hair fibers.

The dog's skin condition improved after removing a tumor that was causing hormone imbalances.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.

Androgens and other hormones affect hair growth and skin conditions like acne.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Extracts improve hair growth in alopecia.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Targeting colon cancer stem cells might lead to better treatment results.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Spironolactone treatment increases the amount of testosterone available in the body.

Apoptosis is essential for human skin development and forming a functional epidermis.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.