Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.
The microneedle device with rapamycin and epigallocatechin gallate effectively promoted hair regrowth in mice.
Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.
Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
Autophagy, a cell process, helps activate hair growth stem cells and promote hair growth by controlling glycolysis, a type of cell metabolism.
Modified HDL can better deliver drugs and genes, potentially improving treatments and reducing side effects.
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.
A woman was allergic to quinine in her anti-hair loss lotion.
Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.
Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.
Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.
Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
mTORC1 signaling needed for quick hair follicle recovery after radiation damage.
A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.
The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
Acne is not a key diagnostic feature for PCOS, postadolescent men with acne may have insulin resistance, melanoma patients often have few moles, tumor size in CSCC indicates higher risk of serious outcomes, and hidradenitis suppurativa is linked to higher risk of heart problems and death.
Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.