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In this study, targeted deletion of the stearoyl-CoA desaturase 1 gene in mice disrupted the epidermal lipid barrier, leading to increased water loss, impaired thermoregulation, and metabolic issues.

In this review, retinoids are highlighted as promising agents for promoting scarless skin regeneration by coordinating cellular and molecular processes that suppress fibrosis, enhance re-epithelialization, promote angiogenesis, and enable hair follicle formation, potentially advancing functional skin repair.

This study found that PDGF-D acts as a potent mitogenic factor in adipose-derived stem cells, enhancing their proliferation, migration, and growth factor expression, suggesting its use as a preconditioning agent for ASC transplantation.

This study highlights that dissecting cellulitis of the scalp affects a diverse racial population and is associated with male sex, metabolic dysfunction, and psychiatric comorbidities, challenging its traditional characterization as primarily a disorder of Black men.

This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.

This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.

This document reviews various studies presented at the Plastic Surgery Research Council (PSRC) Annual Meetings and reports no new research findings; it discusses topics ranging from reconstructive techniques to gender-affirming surgeries.

This study highlights that including scalp dermoscopy in diagnosing patients treated with the Regenera® protocol revealed that expected outcomes were often overestimated for those with poor prognosis.

The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.

This article discusses dissecting cellulitis of the scalp, an uncommon hair condition, and reports no new clinical results; recent terminology adjustments are noted for potential overlaps with other follicular diseases.

This study explored using 3D models derived from reflectance confocal microscopy to better understand and differentiate melanoma on sun-damaged skin, suggesting enhanced diagnostic possibilities.

In this study, epidermal stem cells were found to enhance blood vessel formation and support successful one-step transplantation of tissue-engineered skin in a rat model.

This study observed that a CARASIL mouse model demonstrated abnormal behavior, vascular and cellular changes, and upregulation of the TGF-β/Smad signaling pathway, indicating its potential involvement in CARASIL pathogenesis.

This study reports that the differential expression patterns of three retinaldehyde dehydrogenases suggest a regulated need for retinoic acid synthesis in various organs during late mouse organogenesis.

This review discusses the role of fibroblast heterogeneity in determining skin scarring versus regeneration and reports no new results, highlighting opportunities for developing antiscarring therapies.

This article reviews the complex roles and therapeutic potential of Mesenchymal Stem Cells across various medical applications, emphasizing their anti-inflammatory and tissue repair functions rather than cell replacement or differentiation, and concludes that more precise measurement of their survival and effectiveness is needed.

This review examines the role of adipose-derived stem cells in cancer treatment, particularly for hepatocellular carcinoma, and reports mixed preclinical and clinical findings, underscoring the need for further research.

This study successfully improved methods for isolating, culturing, and purifying rat hair follicle stem cells, demonstrating their high purity, strong proliferation, and potential for adipogenic and osteogenic differentiation in vitro, which could support advancements in tissue engineering.

This study introduced rPanglaoDB, an R package that facilitates the integration of public scRNA-seq datasets to effectively characterize rare cell types, exemplified by generating the first unbiased transcriptome profile of fibrocytes.

The researchers reported that disrupting ATRA signaling by deleting RDHE genes in the hair follicle led to altered hair follicle cycles, composition, and gene expression, indicating RDHEs' role in hair follicle signaling coordination.

This study found that S. scabiei infestation in rabbits leads to epidermal thickening possibly due to apoptosis-related proliferation and keratinization of the skin.

The researchers reported that adipose-derived stem cells from type 2 diabetic mice showed comparable therapeutic effects in wound healing to control cells, despite slightly reduced growth factor secretion and healing promotion.

In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.

This study found that injecting xeno-free, three-dimensional cell masses from human adipose-derived stem cells improved blood perfusion and preserved limb function in mice without causing tumors or toxicity, suggesting potential for treating severe ischemic diseases.

Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.

This study found that gelatin sponges used as scaffolds in rats with deep wounds and periosteal defects enabled regeneration of diverse tissue types, including periosteum, skin, and appendages, highlighting the role of vascular niche formation.

This study found that mouse astrocytes formed cell spheres on agarose surfaces, acquired stem cell-like features, and their derived stem cells effectively differentiated into neurons that helped regenerate damaged nerves.

This review article systematically summarizes current knowledge on using hair follicle neural crest stem cells and their exosomes for repairing peripheral nerve injuries, focusing on the molecular mechanisms and potential applications. The dataset includes comparison tables and diagrams to visually present findings from existing research.

In this study, researchers found that deficiencies in Gsdma1/2/3 significantly inhibited the initiation and progression of cutaneous squamous cell carcinoma (cSCC) in mice, suggesting GSDMA's role in promoting cSCC proliferation and its potential as a therapeutic target.

In this study, a deep neural network model called regX was developed to prioritize driver regulators for cell state transitions by incorporating gene-level regulation and interactions, showing potential therapeutic targets in type 2 diabetes and hair follicle development when applied to single-cell multi-omics data.