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Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Higher androstenedione levels in women with PCOS are linked to more severe symptoms.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Fat stem cells from diabetic mice can still help heal wounds.

Spermidine helps protect against aging by preserving telomere length.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

PCOS is a common hormonal disorder in women that can lead to serious health problems.

A new gene mutation causes insulin resistance in a girl and her mother.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

Stem cell niches support, regulate, and coordinate stem cell functions.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.