13 citations
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December 2001 in “Journal of Investigative Dermatology” This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.
April 2026 in “Journal of Cancer” This review reports that the compound Cepharanthine shows promise as a cancer therapy by inducing cell death, arresting cell growth, inhibiting tumor progression, modulating key oncogenic pathways, and reversing multidrug resistance, suggesting its potential for further investigation in oncology.
6 citations
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May 2023 in “Molecules” In this study, dry powder inhalers containing Cepharanthine were administered to rats with acute lung injury, significantly reducing pulmonary edema, hemorrhage, and inflammatory markers, suggesting its potential as an effective anti-inflammatory treatment when inhaled directly into the lungs.
19 citations
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April 2020 in “Oxidative Medicine and Cellular Longevity” This study provides evidence that Fernblock® upregulates antioxidant pathways in cultured keratinocytes, potentially protecting against damage from fine pollutant particles.
This paper discusses various toxicological properties of diphenyl cresyl phosphate, highlighting its low acute toxicity, potential neurotoxicity linked to o-cresyl phosphate content, and the lack of data for inhalation exposure, but presents no new experimental findings.
42 citations
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February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that PNU 157706 is a highly potent inhibitor of human 5α-reductase enzymes, showing a stronger and longer-lasting antiprostatic effect in rats compared to finasteride.
January 2015 in “Journals & Books Hosting (International Knowledge Sharing Platform)” This study synthesized and evaluated five 6-mercaptopurine derivatives for anticancer activity against three cancer cell lines, detailing the promising results of compound 1.
21 citations
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January 2010 in “JOURNAL OF HEALTH SCIENCE” This study found that abietic acid from pine resin more effectively inhibits testosterone 5α-reductase than several plant extracts, suggesting potential for treating androgen-dependent diseases.
44 citations
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January 2007 in “Biological & pharmaceutical bulletin” This study found that Piper nigrum leaf extract showed in vivo anti-androgenic activity and potent 5α-reductase inhibitory effects, with piperine and (−)-cubebin identified as active components.
115 citations
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August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses the role of cytochrome P450 enzymes in skin metabolism and drug development for skin diseases, highlighting their importance and suggesting further research, but reports no new experimental findings.
21 citations
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September 2019 in “International Journal of Nanomedicine” RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
8 citations
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January 2021 in “Advances in Traditional Medicine” In this study, black tea kombucha with and without MSM significantly improved hair density and length in mice, suggesting its potential as a natural hair regrowth treatment.
3 citations
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January 2017 in “Revista chilena de nutrición” This review highlights that several clinical and epidemiological studies link a diet high in terpenoid compounds with a decreased risk of prostate cancer, supporting the potential use of terpenoids as therapeutic ingredients in treating this disease.
1 citations
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January 2002 in “PubMed” The researchers reported that both finasteride and PM-9 competitively inhibit the 5 alpha-reductase enzyme in P. crustosum broth.
4 citations
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December 2024 in “European Journal of Medicinal Chemistry” This study reported the development of new pyrazole-based MPC inhibitors that effectively inhibit mitochondrial pyruvate transport, showing potential as therapeutic candidates for conditions like metabolic dysfunction-associated steatohepatitis without activating PPARγ.
4 citations
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January 2000 This article discusses recent findings on piedra infections in hair and their keratinolytic activities, but reports no new clinical results.
In this study, researchers successfully synthesized a rigid 3a-arylhexahydropentalene-1,6-dione from the easily accessible starting material cyclopent-2-en-1-one, highlighting a structural motif common in natural products and pharmaceuticals.
37 citations
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December 2020 in “PLANT PHYSIOLOGY” In this study, the researchers identified a temperature-sensitive mutant in Arabidopsis thaliana, showing disrupted root hair formation and altered responses to plant hormone treatments at elevated temperatures.
201 citations
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May 2001 in “Proceedings of the National Academy of Sciences” This study found that transgenic expression of COX-2 in mouse basal keratinocytes causes epidermal hyperplasia and certain dysplastic features at specific body sites.
126 citations
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November 1987 in “The Journal of Pediatrics” This study reports that selenium deficiency in children on long-term total parenteral nutrition may lead to symptoms like erythrocyte macrocytosis and skin and hair depigmentation, which improved with selenium supplementation.
46 citations
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August 2020 in “International Journal of Genomics” This review examines over 271 candidate genes associated with economic traits in goats, highlighting their potential use in genetic markers and future breeding programs, and reports no new experimental results.
15 citations
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February 2014 in “Toxicology Letters” This study found that osthole, a coumarin derivative, demonstrated significantly higher skin accumulation and potential skin irritation compared to coumarin, which showed negligible alterations in protein biomarkers.
8 citations
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September 2021 in “Journal of Cosmetic Dermatology” This review discusses the varied levels of evidence linking nutritional supplements and antioxidants to dermatological disorders, but it reports no new clinical results and highlights the need for rigorous trials.
September 2021 in “Physiology News” This abstract contains only graphical design information and does not report any research findings or conclusions.
January 2011 in “Nuclear Techniques” This study found that lead accumulated in the hair shafts of individuals exposed to mining environments, while iron, copper, and zinc levels remained stable, highlighting the significance of SRXRF micro-analysis for environmental health research.
4 citations
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January 2024 in “Allergy” This study indicates that individuals exposed to PPD mount varying immune responses, with either tolerance, subclinical inflammation, or allergy, suggesting no true non-responders to PPD.
9 citations
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June 2022 in “Reviews in Environmental Science and Bio/Technology” This review discusses the industrial applications of maritime pine by-products, emphasizing their antioxidant and antimicrobial properties, and suggests innovation opportunities in a circular economy context; it reports no new results.
October 2025 in “Scientific Reports” This study found that grape leaves, especially from the 'Razaki' white cultivar, are rich in phenolic compounds and flavonols, suggesting potential use in developing functional products.
2 citations
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July 1982 in “British Journal of Dermatology” This study reports that retinol acetate inhibited the pro-oxidant effects of benoxaprofen on polymorphonuclear leucocytes in vitro.