April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that a shampoo containing a 6-active ingredient complex increased β-Catenin production in human hair follicle dermal papilla cells to levels comparable to Finasteride, suggesting potential for promoting hair growth. It also showed good cleaning efficacy, volume, and shine in a sensorial study.
This review summarizes recent genetic research on hidradenitis suppurativa, highlighting potential therapeutic targets and genetic mutations, but reports no new clinical findings.
December 2019 in “International journal of scientific research in science and technology” This study developed and validated a simple and cost-effective spectrophotometric method to accurately determine Aminexil in cosmetic formulations containing niacinamide and pyridoxine.
December 2017 in “JURNAL FARMANESIA” In this study, the researchers found that using dragon fruit peel extract in a gray hair dye formulation, along with specific adjuvants, produced a dark black color on gray hair, demonstrating its potential as a natural colorant alternative to synthetic dyes.
January 2016 in “Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver” This study found that novel biodegradable nanocarriers with highly hydrophobic cores significantly increased the solubility and sustained release of hydrophobic drugs and dyes, showing promise for drug delivery applications.
April 2012 in “KSBB Journal” This study suggests that specific structural features of minoxidil analogs, such as hydrophobic and hydrogen bond field contributions, are key to enhancing lysyl hydroxylase inhibitory activity, which could inform future hair growth treatments.
January 2010 in “Yearbook of Endocrinology” Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
The authors concluded that capecitabine and high-dose toremifene may be an effective treatment option for patients unable to undergo anthracycline or taxane therapies, based on one woman's cancer management.
This review discusses the mechanisms of cell death in skin-associated processes and highlights potential therapeutic opportunities for targeting cell death to treat inflammatory skin diseases, but reports no new clinical results.
December 1989 in “The Journal of Dermatologic Surgery and Oncology” New techniques and findings in dermatologic surgery show improved pain management, safer liposuction, better hair transplantation, and effective treatments for skin conditions.
February 2022 in “Scientia Pharmaceutica” This study validated that six out of seven tested topical formulations for alopecia are compatible for 6-month use, suggesting they may be practical for compounding pharmacies.
202 citations
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August 2017 in “Nature cell biology” This study found that glycolytic metabolism and lactate production are crucial for hair follicle stem cell activation, and manipulating these processes can stimulate the hair cycle.
165 citations
,
January 2014 in “Dermatology Research and Practice” This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.
165 citations
,
July 1992 in “Annals of Internal Medicine” This editorial discusses the potential health risks of herbal preparations, highlighting a case of hepatotoxicity in a child due to pyrrolizidine alkaloids in a herbal tea; it reports no new results.
66 citations
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February 2010 in “CrystEngComm” Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.
49 citations
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January 1991 in “Food and chemical toxicology” In this study, zinc chloride was found to be severely irritant to the skin in rabbit, guinea-pig, and mouse models, while zinc oxide, zinc sulphate, zinc pyrithione, and zinc undecylenate showed minimal to no irritancy.
46 citations
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September 2011 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that certain zinc pyrithione shampoos effectively deliver antifungal agents to the scalp's follicular infundibulum, correlating with reduced Malassezia populations, likely influenced by particle size optimizing such delivery.
40 citations
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January 2018 in “International journal of trichology” This article reviews the relationship between scalp conditions and hair health, suggesting that shampoos with Malassezia inhibitory agents may help reduce premature hair loss, but it presents no new clinical results.
35 citations
,
January 2006 in “Journal of Dermatological Treatment” This review found little evidence supporting zinc as a first-line treatment for dermatological conditions, except in cases of systemic zinc deficiency, and suggests further research is needed.
24 citations
,
November 2015 in “International Journal of Cosmetic Science” This study demonstrated that oxidative stress contributes to dandruff, and using a potentiated ZPT shampoo improves scalp and hair condition by reducing oxidative stress.
16 citations
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May 2017 in “Journal of cosmetic dermatology” In this clinical study, the use of potentiated zinc pyrithione shampoo improved scalp health and hair surface characteristics, suggesting that unhealthy scalp conditions may negatively impact pre-emergent hair's cuticle surface.
10 citations
,
January 2016 in “Global Dermatology” This study observed that zinc deficiency in humans and mice was associated with diminished allergic contact dermatitis but increased severity and duration of irritant contact dermatitis.
6 citations
,
August 2021 in “International Journal of Cosmetic Science” This study concluded that a regimen containing functional antioxidants and barrier-enhancing agents reduced hair shedding and increased perceived hair fullness in participants with self-perceived hair thinning over 24 weeks.
4 citations
,
February 2018 in “Jurnal teknologi” This study found that Kaempferia galanga ethanolic extract has potential as an antifungal agent in an oil-in-water cream formulation, exhibiting stable physicochemical properties in laboratory tests.
2 citations
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January 2025 in “International Journal of Cosmetic Science” In this study, dandruff treatment with anti-dandruff shampoos was found to effectively reduce symptoms and enhance emotional wellbeing, indirectly improving daily functioning by alleviating scalp-related emotional distress, though it did not affect self-esteem.
2 citations
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July 2021 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses hair shaft disorders, noting the lack of specific treatments and recommending general care practices to prevent hair damage, with some improvement possible during puberty or with treatments like minoxidil.
1 citations
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April 2025 in “Cureus” In this in vitro study, pretreatment with Dead Sea water and saline magnetized water reduced UVB-induced DNA damage and inflammation markers in human keratinocyte cells, primarily through autophagy activation, suggesting potential use in topical products to prevent skin damage from UV exposure.
1 citations
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September 2011 in “British Journal of Dermatology” This review discusses advances in understanding the role of Malassezia in seborrhoeic dermatitis and dandruff, highlighting the significance of the hair follicle infundibulum and the action of zinc pyrithione, but reports no new clinical results.
The researchers presented a rare case of a four-year-old developing scarring alopecia after a two-week ICU stay, highlighting the challenge of diagnosing pressure alopecia in children and the crucial role of early detection and trichoscopy in preventing permanent hair loss.
May 2026 in “International Journal of Pharmaceutical Research and Development” This abstract explains that dandruff can be treated using either chemical-based or herbal anti-dandruff shampoos, with both types containing antibacterial and antifungal ingredients to reduce scalp flakiness and eliminate fungi.