Blackness and Philosophy: Reply to Gannett, Outlaw, Taylor, and Velazco y Trianosky

The document discussed the role of cell death in skin homeostasis, highlighting its importance in recovery from injury and infection, and its regulation of barrier function and immunity. It noted that while cell death can provoke inflammation through the release of cell contents, excessive or poorly regulated cell death contributes to cutaneous inflammation. The review outlined various cell death mechanisms, including apoptosis, necroptosis, pyroptosis, NETosis, and cornification, and examined their roles in skin inflammation and disease. It also explored therapeutic opportunities for targeting cell death processes to treat inflammatory skin diseases, with drug development programs already in progress.