Blackness and Philosophy: Reply to Gannett, Outlaw, Taylor, and Velazco y Trianosky
January 2005
Studysummary This review discusses the mechanisms of cell death in skin-associated processes and highlights potential therapeutic opportunities for targeting cell death to treat inflammatory skin diseases, but reports no new clinical results.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document discussed the role of cell death in skin homeostasis, highlighting its importance in recovery from injury and infection, and its regulation of barrier function and immunity. It noted that while cell death can provoke inflammation through the release of cell contents, excessive or poorly regulated cell death contributes to cutaneous inflammation. The review outlined various cell death mechanisms, including apoptosis, necroptosis, pyroptosis, NETosis, and cornification, and examined their roles in skin inflammation and disease. It also explored therapeutic opportunities for targeting cell death processes to treat inflammatory skin diseases, with drug development programs already in progress.
