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Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.

Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.

The document emphasizes the need for primary care providers to understand and care for African American children's hair and skin to boost their self-esteem.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

Temporal hair loss relates to overall scalp hair loss in women.

Women of color in Northern Manhattan view hair care as important to their identity and culture, and education on harmful chemicals in hair products is needed.

Young adults with hair loss face higher risk of stiff arteries.

The document explains various skin conditions and their treatments.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

Understanding how acne develops in different diseases could lead to new treatments.

Hair and nails can show hormone changes during puberty in dogs.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.