9 citations
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October 2019 in “Dermatologic Therapy” This study observed that oral tofacitinib was reasonably well-tolerated but had limited efficacy in treating alopecia areata, with a clinical response seen in 41.4% of patients over six months.
October 2025 in “Biomedicines” This study suggests that Terminalia chebula fruit extract may promote hair growth in androgenetic alopecia by activating specific signaling pathways and inhibiting 5α-reductase, showing effectiveness comparable to finasteride.
69 citations
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August 2006 in “Behavior Therapy” This study found that group behavior therapy for trichotillomania led to greater short-term symptom improvement compared to supportive therapy, but did not achieve clinically significant changes or prevent relapse over six months.
January 2003 in “Jiefangjun yixue zazhi” In this study, the researchers observed that the expression of certain growth factors and their receptors increases with gestational age, implying a role in skin development, structure maintenance, and wound healing.
January 2021 in “Our Dermatology Online” This case report describes a patient with alopecia universalis who had an excellent and persistent response to oral tofacitinib treatment after one year.
October 2025 in “International Journal of Risk & Safety in Medicine” In this case study, a 5-year-old girl with alopecia areata and atopic dermatitis that were unresponsive to previous treatments achieved substantial improvement with long-term tofacitinib, highlighting its potential safety and efficacy in managing both conditions concurrently.
3 citations
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June 2002 in “Transgenic Research” This study suggests that inducible transgenic mice showing hair follicle changes similar to telogen effluvium in humans might serve as a useful model for understanding this type of hair loss.
January 2018 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Telogen effluvium is a condition that causes temporary hair loss due to stress or shock to the body.
January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Telogen effluvium is a condition that causes temporary hair loss due to stress or shock to the body.
January 1998 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Telogen effluvium is a condition that causes temporary hair loss due to stress or shock to the body.
1 citations
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August 2025 in “Bioengineering” In this study, the combination of full-thickness skin column grafts and the TSN6 peptide improved wound healing quality in pigs by enhancing epidermal maturation compared to other treatments.
September 2023 in “Journal of the American Academy of Dermatology” CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.
28 citations
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December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This review summarizes findings on the long-term use of tofacitinib for severe alopecia areata, reporting its potential as a promising treatment option.
July 2024 in “Journal of Investigative Dermatology” ITK inhibitors may effectively treat alopecia areata.
January 2013 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Telogen effluvium is a condition that causes temporary hair loss.
3 citations
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October 1994 in “Journal of Dermatological Science” This study developed a novel monoclonal antibody, TYHF-1, which specifically reacts with hair keratins but not with epidermal keratins or various other tissue cells.
April 2025 in “Indian Journal of Paediatric Dermatology” This case report describes an 8-year-old male with tinea capitis and Trichorrhexis invaginata, who showed significant improvement after treatment with oral micronized griseofulvin.
11 citations
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January 1989 This case report describes two patients with trichothiodystrophy who exhibited a different pattern of hair protein composition changes, suggesting a subgroup of TTD characterized by partial loss of high-sulfur proteins without significant alteration in their amino acid composition.
1 citations
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April 2018 in “Journal of Investigative Dermatology” This open-label study found that oral tofacitinib led to significant hair regrowth in patients with moderate-to-severe alopecia areata, supported by changes in gene expression and T cell dynamics.
105 citations
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February 1996 in “Journal of biological chemistry/The Journal of biological chemistry” In this study, sequences upstream of the TGM3 gene were found to regulate epithelial-specific gene expression in keratinocytes, suggesting potential applications in gene therapy.
January 1994 in “JAPANESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS” Testosterone and fleece-flower root affect mouse hair growth.
10 citations
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May 2020 in “Dermatologic therapy” In this study, a patient with recalcitrant lichen planopilaris and frontal fibrosing alopecia showed significant improvement after receiving four doses of the interleukin-23 monoclonal antibody tildrakizumab.
2 citations
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February 2018 in “Journal of dermatology & cosmetology” This article discusses triangular temporal alopecia, highlighting dermoscopy's role in diagnosis and the limited therapeutic options, without reporting new clinical results.
3 citations
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January 2025 in “International Journal of Biological Macromolecules” This study found that a microneedle patch containing tofacitinib-loaded nanoparticles significantly increased hair follicle numbers and promoted hair regeneration with less drug compared to daily topical tofacitinib, suggesting it may be an effective strategy for alopecia treatment by reducing dosing frequency and enhancing drug delivery.
1 citations
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November 2024 in “Frontiers in Immunology” This study provides an analysis of global publications on TLS, offering insights into the role of TLS in immunotherapy and suggesting future research directions.
26 citations
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September 2023 in “Journal of Allergy and Clinical Immunology” Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
16 citations
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December 2019 in “Animals” In this study, cashmere goats engineered to overexpress the Tβ4 gene in hair follicles produced more cashmere, indicating that Tβ4 promotes secondary hair follicle development and enhances yield.
July 2023 in “Journal of Microbiology and Biotechnology” This study found that oral administration of Terminalia bellirica enhanced hair growth in testosterone-suppressed conditions in both human cell and mouse models, outperforming finasteride, a current commercial hair loss treatment.
4 citations
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February 2023 in “International Journal of Stem Cells” The FTO gene hinders stem cells in hair follicles from becoming pigment cells.
4 citations
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May 2019 in “Sultan Qaboos University Medical Journal” Tofacitinib helped regrow hair in a patient with severe hair loss and improved their quality of life without side effects.