TLDR Oral tofacitinib successfully treated a girl's severe skin and hair conditions.
A 5-year-old girl with therapy-resistant alopecia areata and atopic dermatitis was successfully treated with oral tofacitinib, initially at 5 mg once daily, then increased to 5 mg twice daily due to inadequate response. This treatment led to complete hair regrowth, except for the ophiasis pattern, and full clearance of atopic dermatitis. The case highlights the long-term safety and efficacy of tofacitinib for managing these concurrent dermatological conditions, despite limited case reports on its use for both conditions simultaneously.
September 2023 in “Acta dermato-venereologica” Tofacitinib is a safe and effective treatment for hair loss in children with Alopecia Areata.
26 citations
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October 2020 in “Pediatric Dermatology” Oral tofacitinib may effectively treat hair loss in children with alopecia areata.
16 citations
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June 2018 in “JAAD case reports” A JAK inhibitor improved both severe hair loss and chronic skin disease in one patient.
November 2023 in “Indian Dermatology Online Journal” Tofacitinib was effective for severe, treatment-resistant hair loss without side effects.
Tofacitinib helped a woman with total-body hair loss grow her hair back.
7 citations
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March 2021 in “Journal of the American Academy of Dermatology” Tofacitinib can regrow hair in alopecia areata patients, but some may experience flares during treatment.
16 citations
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July 2017 in “Rheumatology and Therapy” Tofacitinib, a medication for arthritis, showed potential for treating severe hair loss in a small Brazilian case series, but more research is needed.
16 citations
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January 2017 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” A patient with complete hair loss regrew all her hair using tofacitinib.
