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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Targeted cancer therapies often cause serious skin problems that need careful management.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Use minoxidil for hair loss treatment; assess results after 6 months.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Tofacitinib may help treat severe hair loss, but more research is needed.

TSH is usually the only test needed to check thyroid function in primary care.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.