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Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

CAP1/Prss8 does not activate PAR2 or inhibit PN-1.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The gene Prss53 affects hair shape and bone development in rabbits.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

CAP1 decreases the expression of a hair-related protein in young Tan sheep's skin.

Higher EULAR/ACR scores in SLE patients predict more organ damage.

Excluding alopecia and mucous membrane components from the CLASI-A score reduces its effectiveness in capturing important disease activity.

FOXN1 gene variants cause low T cells and immune issues from birth.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Researchers identified specific genes that are important for mouse skin cell development and healing.

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

Genomic approach finds new possible treatments for hair loss.

A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.

Some alopecia treatments might help treat COVID-19, but more research is needed.

Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.