research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
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research The Variable Cell
Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
research Follicular Liposomal Delivery Systems
New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
research Treatment of Alopecia Areata: What Is New on the Horizon?
New treatments for alopecia areata may target specific immune cells and pathways involved in hair loss.
research Active Ingredients for Treating Androgenetic Alopecia Provided by Different Brands
The document concluded that home treatments are needed for hair loss control, but professionals should better understand how these treatments work.
research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research Recent Developments in the Treatment of Obesity with Particular Reference to Semistarvation Ketogenic Regimens
The document concludes that a high-protein, low-carb diet can lead to significant weight loss but requires caution and further research.
research Pomiferin: A Potent Stimulant of Extracellular Matrix Proteins
Pomiferin may improve skin and scalp health by boosting important protein expression.
research News in Brief
Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.
research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
research Development and Validation of Androgen-Induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents
The mouse models are effective for testing new hair loss treatments.
research Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research
New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.
research PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
research RNA Sequence Analysis of Dermal Papilla Cells’ Regeneration in 3D Culture
3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
research Molecular Genetics of Inherited Disorders of Epidermal Keratins
Mutations in keratin genes cause skin disorders, but new treatments show promise.
research Learning From Nudity: Lessons From The Nude Phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Hair: Its Structure and Response to Cosmetic Preparations
Hair can be damaged by daily routines, but protein-based products can protect and improve it.
research Inherited Epidermolysis Bullosa: Clinical and Therapeutic Aspects
The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.
research Non-Viral Delivery of the CRISPR/Cas System: DNA Versus RNA Versus RNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Computational Drug Discovery in Chemotherapy-Induced Alopecia via Text Mining and Biomedical Databases
Computational tools identified 29 drugs that could potentially target 19 genes involved in chemotherapy-induced hair loss, which could lead to more effective treatments.
research Autoantigen Screening in C3H/HeJ Mouse Model of Alopecia Areata Revealed High Antigenicity of Melanocyte-Associated Antigen Epitopes
Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.
research Hutchinson-Gilford Syndrome: History, Causes, Phenotype and Research Advances
Hutchinson-Gilford Progeria Syndrome causes rapid aging from a genetic mutation, with no cure but ongoing research into potential treatments.
research Epidermolysis Bullosa
Epidermolysis bullosa is an inherited condition causing fragile skin with no cure, managed by wound care and experimental treatments show promise.
research Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages
Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.
research Response of Distinct Human Dermal Fibroblast Lineages to Visible Radiation: Potential for Differential Light-Based Therapy
Different types of human skin cells respond uniquely to various colors and doses of light, which could lead to specialized light treatments for skin conditions.
research Targeting Receptor–Regulator Interactions
New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
research A New Way to Restore Tumor Suppressor Function
New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.
research News in Brief
Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.
research The Physical and Chemical Disruption of Human Hair After Bleaching – Studies by Transmission Electron Microscopy and Redox Proteomics
Bleaching hair causes severe structural and chemical damage, including protein loss and oxidation.