March 2014 in “The Journal of Urology” This study observed that long-term treatment with 5ARIs in men with LUTS/BPH was linked to worsening sexual function, whereas doxazosin alone had minimal negative impact.
June 2011 in “Oncology times” This article covers discussions from the Society of Urologic Oncology Annual Meeting outlining that new therapies, such as Provenge, Prostvac, and denosumab, are making the treatment of advanced prostate cancer more complex but may offer extended survival benefits.
12 citations
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December 2015 in “F1000Research” This article discusses advancements and future directions in the treatment of benign prostatic hyperplasia, highlighting ongoing clinical trials of novel techniques, but it reports no new clinical results.
2 citations
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April 2021 in “Canadian Journal of Urology” This review summarizes existing studies on 5-alpha reductase inhibitors, noting their effectiveness in reducing prostate volume and cancer risk but highlighting an increased risk of higher grade prostate cancer.
This study found that PLX, a mixture of tomato extract and chitooligosaccharide, may reduce prostate weight in testosterone-induced BPH in rats, suggesting it could act as a 5α-reductase inhibitor.
6 citations
,
January 2003 in “PubMed” Finasteride reduces prostate size and symptoms with few side effects.
24 citations
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June 2013 in “Expert opinion on pharmacotherapy” This review found dutasteride to be effective, safe, and well-tolerated for treating symptomatic BPH and provides expert commentary on its use, though the relationship with high-grade prostate cancer remains unclear.
6 citations
,
June 2014 in “PubMed” This study concluded that transurethral seminal vesiculoscopy combined with finasteride is a safe and effective treatment for recurrent hemospermia in the observed patients.
30 citations
,
June 2010 in “Endocrine Related Cancer” In this study, dutasteride more effectively reduced prostate cancer cell viability than finasteride in vitro, but did not significantly alter the angiogenic response.
105 citations
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January 2004 in “The Journal of Urology” This study found that finasteride significantly improved symptoms in CP/CPPS patients, except for voiding, unlike saw palmetto which showed no long-term benefits.
October 2006 in “Urology” The document aimed to understand how certain treatments affect blood vessel growth in rat prostates.
April 2018 in “The Journal of Urology” This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.
57 citations
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January 1986 in “The Prostate” This article discusses the role of dihydrotestosterone in human prostatic adenocarcinoma growth and suggests that 6-methyleneprogesterone could be used to inhibit DHT for treating hormone-responsive prostate cancer, without new clinical findings.
3 citations
,
December 2016 in “Der Urologe”
21 citations
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October 2015 in “Current Drug Targets” This review discusses the comparative efficacy of dutasteride and finasteride for benign prostatic hyperplasia, reporting that while symptom improvements are similar, dutasteride may reduce prostate surgery risk and acute urinary retention more effectively.
January 2004 in “Zhongguo yiyuan yongyao pingjia yu fenxi” This study found that combining tamsulosin with finasteride was the most cost-effective treatment for mild to moderate BPH among the regimens tested.
46 citations
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January 2005 in “PubMed” This paper discusses risk factors and prevention strategies for acute urinary retention secondary to benign prostatic hyperplasia, emphasizing the role of PSA levels and the benefits of medications like finasteride and alpha-blockers, but reports no new clinical results.
March 2009 in “The Journal of Urology” This research concludes that finasteride significantly reduces dihydrotestosterone levels and prostate size in men with BPH and may improve urinary symptoms, with greater baseline prostate size predicting more pronounced benefits compared to placebo.
January 2025 in “Investigative and Clinical Urology” This study found that after 12 weeks of taking the trial product SHPro®, participants reported improvements in prostate symptom scores and erectile function, with confirmed safety.
6 citations
,
March 2005 in “The Journal of Urology” This study evaluates finasteride's safety and efficacy for treating male chronic pelvic pain syndrome, but the abstract does not report any results.
November 2005 in “The Journal of Urology” This paper discusses the effect of dutasteride on prostate cancer detection in men with benign prostatic hyperplasia but provides no new clinical results.
November 2005 in “The Journal of Urology” This erratum addresses the long-term effects of finasteride on prostate-specific antigen levels but reports no new research findings.
February 2013 in “Americanae (AECID Library)” In this study, finasteride exposure in human prostatic cell lines did not affect cell proliferation but significantly reduced MMP activity and increased TIMP expression, potentially inhibiting tumor cell invasion and metastasis.
January 2010 in “Journal of Oriental Medicine” This study found that Phellodendri Cortex Ex may reduce prostate tissue damage and inhibit $5{\alpha}$-reductase gene expression in a rat model of benign prostatic hyperplasia, suggesting potential therapeutic benefits.
33 citations
,
April 2009 in “Journal of the American College of Certified Wound Specialists” This narrative review discusses the advantages of bidirectional barbed sutures in wound closure, such as faster placement and no need for knots, but reports no new clinical results.
26 citations
,
August 2016 in “Actas Dermo-Sifiliográficas” This study found that men with frontal fibrosing alopecia were more likely to have facial papules, androgenetic alopecia, and body hair loss compared to women, with the average patient age being higher than in other series, potentially explaining these differences.
2 citations
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January 2024 in “Wiadomości Lekarskie” This study suggests that artificial intelligence could significantly enhance histology education for medical and dental students, but its implementation faces challenges like cost, accuracy, and ethical considerations.
1 citations
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January 2024 in “Wiadomości Lekarskie” This study evaluated a new computer-aided detection system for identifying Breast Arterial Calcification in mammograms, achieving 70% accuracy, but highlighted the need for a larger dataset to explore its relationship with cardiovascular diseases.
January 2024 in “Wiadomości Lekarskie” This source reports that clinical trials using advanced Deep Brain Stimulation systems, augmented with AI to integrate kinematic data, eye tracking, and cognitive assessments, show promise in improving diagnostic accuracy and monitoring symptoms for patients with Parkinson's disease.
January 2024 in “Wiadomości Lekarskie” In this retrospective study conducted at Grodno Regional Children's Hospital, researchers found that children in western Belarus showed more severe COVID-19 symptoms in 2021 compared to 2020, with urban children primarily affected, and family contact emerging as the most common source of infection.