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July 2024 in “The International Journal of Medical Science and Health Research” The literature review concluded that while 5α-reductase inhibitors hold promise for managing prostate cancer, they raise significant safety concerns regarding their association with high-grade tumors and mortality, highlighting the need for careful consideration in their clinical use.
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January 2024 in “Scandinavian Journal of Public Health” This review offers a useful summary and comparison of how different diseases impact society, underscoring the importance of considering social impact in healthcare policymaking and resource allocation.
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December 2023 in “Curēus” This literature review identified that phosphodiesterase 5 inhibitors, such as Tadalafil, are highly effective in improving lower urinary tract symptoms associated with benign prostatic hyperplasia, while the efficacy of saw palmetto remains inconsistent.
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January 2018 in “AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES” In this study, the ethanol extract of Zapoteca portoricensis stem significantly reduced markers of testosterone-induced benign prostate hyperplasia in male albino rats without harming liver and kidney function.
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June 2010 in “Mayo Clinic Proceedings” This article reviews the Clinical Pearls presentation format introduced at the American College of Physicians' 2001 meeting for its effectiveness in applying practical clinical tips, but provides no new empirical results.
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July 1997 in “Inpharma Weekly” Finasteride improves hair growth and satisfaction in men with male pattern baldness but may cause sexual side effects.
March 2026 in “Seven Editora eBooks” This study systematically reviewed the use of topical testosterone products such as creams, gels, and patches, finding they effectively raise serum testosterone but pose significant systemic risks like acne and gynecomastia, necessitating careful medical oversight.
July 2025 in “Frontiers in Bioengineering and Biotechnology” This study reports that despite advancements in tissue engineering and biomaterials, translating laboratory findings into effective clinical treatments for urethral reconstruction remains inadequate due to lack of standardization and short clinical trial follow-ups.
This study examined data from the FDA Adverse Event Reporting System and found that finasteride use is linked with both known and previously unlisted adverse events, such as erectile dysfunction and post-5α reductase inhibitor syndrome, with variations observed by age and sex.
March 2025 in “Journal of Neonatal Surgery” This survey paper analyzes advancements in robotic surgery, highlighting the integration of autonomous systems in medical practices and their impact on precision and patient outcomes, while discussing benefits, challenges, and ethical considerations, with a focus on applications from neonatal to neurosurgical procedures.
This review explores how technologies like telemedicine, wearable devices, bioengineering, and digital therapeutics are enhancing the management of sexual dysfunction in patients with chronic diseases by offering personalized and accessible solutions, although traditional approaches often fall short.
January 2025 in “Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)” This study describes how robotic surgery has been widely adopted across various specialties in Hungary, showing benefits like lower complication rates and quicker recovery times, but also acknowledges challenges such as high costs and extended learning periods.
This study suggests that bioactives like Curcumin, Quercetin, and "Tulsi" may relieve chemotherapy-induced adverse drug reactions in cancer patients, potentially reducing resistance and recurrence.
March 2024 in “Research Square (Research Square)” This study found no significant benefit of platelet-rich plasma injections over placebo in improving erectile function in patients with mild to moderate erectile dysfunction.
In this review of autonomous robotic surgery, the authors explore the integration of AI and machine learning in surgical procedures, detailing both the advancements and challenges of these technologies, including ethical concerns and current regulatory frameworks.
This monograph reviews the historical and contemporary use of pomegranate in medicine, detailing its chemical components and applications across various medical fields including oncology, dentistry, and urology.
November 2023 in “Research Square (Research Square)” This animal study found that finasteride, a 5-alpha reductase type 2 inhibitor, decreased dihydrotestosterone levels and c-Fos protein activation in the rat brain, but these effects may diminish after discontinuing the drug.
November 2022 in “CARDIOMETRY” This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.
April 2022 in “Diabetes Therapy” In this case report, the researchers emphasize the importance of regular prostate exams and PSA tests for diabetic men, including those who are hypogonadal, because prostate cancer development is linked to intraprostatic dihydrotestosterone levels, not serum testosterone levels.
October 2020 in “Cirugía y cirujanos” This study found that severe obesity is positively associated with more severe lower urinary tract symptoms compared to moderate obesity in patients with prostatic enlargement.
January 2019 in “Springer eBooks” Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.
February 2018 in “The Journal of Sexual Medicine” The researchers reported that using Natesto® testosterone gel improved erectile function and mood in hypogonadal men over a 90-day period.
April 2017 in “Austin Journal of Cancer and Clinical Research” This article reviews the role and controversies of 5α-reductase inhibitors like finasteride and dutasteride in managing prostate cancer, without presenting new research results.
March 2017 in “BJU international” This article discusses the BJUI's strategies to support urology-related clinical trials but reports no new experimental results; the authors emphasize the importance of rigorous trial design and reporting standards.
December 2016 in “University of Birmingham Institutional Research Archive (University of Birmingham)” This study suggests that the adrenal gland may contribute to prostate cancer treatment resistance and indicates potential steroid production or dependency in ovarian cancer.
March 2016 in “National Repository of Dissertations in Serbia” This study found that dutasteride is more cost-effective compared to finasteride for treating benign prostatic hyperplasia in Montenegro, justifying its funding by the national health insurance fund.
This review suggests that finasteride at 1 mg/day reduces PSA levels similarly to 5 mg/day, but differences in prostate dihydrotestosterone levels may affect prostate cancer diagnosis and prevention.
April 2015 in “Andrology” This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.
September 2012 in “African Journal of Urology” This review describes the clinical features of testosterone deficiency syndrome in aging men but reports no new experimental findings, highlighting the need for clinical recognition and treatment of TDS.
April 2012 in “The Journal of Urology” Eating more omega-3 and less omega-6 fatty acids may lower the risk of developing prostate cancer.