TLDR The document aimed to understand how certain treatments affect blood vessel growth in rat prostates.
The document reviewed the effects of Finasteride, flutamide, cyproterone, and castration on rat prostate vascularization, in the context of benign prostatic hyperplasia (BPH) and prostate cancer, both of which were associated with neovascularization. The study aimed to understand how these treatments influenced the vascularization of the prostate in rats, potentially offering insights into therapeutic approaches for conditions like BPH and prostate cancer. However, specific results or conclusions from the study were not provided in the summary.
218 citations
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December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
24 citations
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January 2001 in “Dermatologic clinics” Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.
26 citations
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November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry” Treatment during development affects hormone balance and sexual behavior in male rats.
32 citations
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November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
23 citations
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July 1993 in “Pharmacotherapy” Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
