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Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

A new method was developed to make finasteride for treating hair loss.

Older men should openly discuss sexual health with doctors to improve their quality of life.

Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Young and adult hamsters both respond similarly to testosterone and finasteride treatments, but young hamsters aren't good for testing the inhibitory activity of a specific enzyme.

Androgen deprivation therapy might be better for preventing COVID-19 than treating it.

AGA affects many, progresses differently, and early treatment is crucial.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.

Dosing time affects finasteride's effectiveness and safety in rats.

Omega-6 fats in certain cells boost male hormone production.

Men with certain types of baldness at age 45 may have a higher risk of colon cancer and colorectal adenoma.

Balding and low testosterone increase risk of urinary stones.

Finasteride 5 mg effectively reduces urinary symptoms and PSA levels in men with enlarged prostates, with few sexual side effects.

Case-only trees and random forests improve predictions of treatment effects in clinical trials.

Finasteride significantly reduces fertility in male rats.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Male hormones may make COVID-19 worse, while substances that block these hormones could lessen symptoms.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

There's no link between hair loss type androgenic alopecia and benign prostatic hyperplasia, but early hair loss and family history can mean more severe alopecia.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

Finasteride may cause breast enlargement, low testosterone a risk factor.

A new compound that could treat various androgen-related conditions was created and analyzed.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

Finasteride treats hair loss but may cause side effects like low libido and dizziness.

Finasteride and dutasteride may lower melanoma risk, with teenage acne possibly indicating higher risk.