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The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Cetuximab can cause eyelash growth, which is rare but manageable.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

The document concludes that better research methods are needed in men's sexual health to provide stronger evidence and improve patient care.

New treatments and diagnostic methods for urological conditions show promise, but some lack sufficient accuracy for clinical use.

Prescriptions for 5-alpha reductase inhibitors dropped significantly after the FDA's safety warning, especially for men with benign prostatic hyperplasia.

A new method accurately measures nine specific hormones in human blood.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Testosterone may influence COVID-19 severity and outcomes.

Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.

Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Continued research and awareness are needed to improve treatments for androgen-dependent diseases.

Minoxidil can reduce functions related to androgen receptors.

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.

High uric acid can cause health issues, so managing it with lifestyle changes is important.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.