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This study found that Ocimum basilicum L. showed the highest 5α-reductase inhibitory activity among ten Thai plants, despite no correlation between enzyme inhibition and total phenolic content.

This study evaluated 32 marker compounds from natural herbal extracts and found that four of them, honokiol, isoalantolactone, broussochalcone A, and 3-deoxysappanone B, can induce hair growth, suggesting a potential natural treatment for hair loss.

In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.

This study highlights the potential of cosmetic products combining fibroblast growth factors and antioxidants like thioproline, ergothioneine, silymarin, and rosmarinic acid, to mitigate skin aging by reducing oxidative stress and enhancing cellular protection in the skin.

This study found that GD-23, a dipeptide ligand of TSPO, exhibited an anxiolytic effect in the elevated plus maze test, which was inhibited by selective neurosteroid synthesis inhibitors, suggesting a neurosteroidogenic mechanism.

This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.

This letter to the editor about prostaglandins in androgenetic alopecia in men and women reports no new research findings.

This study found that kukui nut oil (AMS oil) promotes hair growth in human hair follicle cultures by increasing PGF2α levels and activating Nrf2 signaling, and a human trial confirmed its efficacy in enhancing eyelash growth.

This study found that Placenderm®, a porcine placenta peptide, may promote hair follicle regeneration and enhance hair growth in mice by balancing growth-promoting and inhibitory factors.

This study found that procyanidin B-3, a compound isolated from barley extract, may promote hair growth by enhancing hair epithelial cell growth and counteracting TGF-β1's growth-inhibiting effects in vitro and in vivo.

Green algae can break down finasteride, reducing environmental harm.

This study reported that while no synthesized compounds surpassed finasteride in 5α-reductase inhibitory activity, certain 4-azasteroid-2-oximes exhibited notable inhibition.

In this study using rat models, researchers developed a Pluronic@F-127 hydrogel to deliver the flavonoid pectolinarin, finding it accelerates wound healing and reduces scar formation by enhancing cell migration, proliferation, and antioxidant activity.

A new compound that could treat various androgen-related conditions was created and analyzed.

This review discusses the potential skin care benefits of non-denatured soybean extracts, including skin lightening and UV protection, but reports no clinical results.

In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.

This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

Estetrol may help prevent hair loss and support hair growth in women.

A peptide in shampoo can promote hair growth and improve hair condition.

In this study, procyanidin B-2 and C-1 were found to promote hair growth by selectively inhibiting protein kinase C, supporting their potential use for hair-growing activity.

This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.

SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.

The researchers reported that shiitake mushroom, buckwheat, soybean, cypress, and seaweed fulvescens showed potential as safe and effective natural ingredients for scalp care and scaling due to their antioxidative and antimicrobial properties.

FOL-005 peptide may help treat excessive hair growth safely.

This study found that the ethyl acetate extract of Fagraea berteroana fruits and its fraction FEAE-F0 promoted cell proliferation and modulated gene expression in hair follicle cells, suggesting potential for hair growth stimulation.

This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.

This study suggests that natural molecules like curcumin, EGCG, barringtozenol, and finasteride may be effective inhibitors for VEGFR, potentially offering a cancer chemoprevention alternative to pazopanib.