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Minoxidil can reduce functions related to androgen receptors.

Certain IL-18 gene variations may increase the risk of alopecia areata.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

New genetic locations explain much of hair color variation in Europeans.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.

A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

ERG increases SOX9, promoting prostate cancer growth and invasion.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

Cannabinoids may help treat various skin conditions.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

Significant progress was made in understanding PXE, but effective treatments are still needed.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

IL-4 gene variation may increase the risk of alopecia areata in Turkish people.

More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Activating Nrf2 can help protect against hearing loss.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Allopregnanolone changes gene expression in glioblastoma cells.