5 citations
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November 2017 in “Asian Journal of Beauty and Cosmetology” This study found that sinapic acid demonstrated antioxidant and anti-inflammatory effects against UVB-induced damage in human keratinocytes, suggesting its potential as an anti-aging cosmetic ingredient.
September 2022 in “International journal of pharmaceutical quality assurance” This study concluded that sodium lauryl sulfate is very toxic to hair, damaging its structure, while natural conditioners help protect hair integrity and improve consistency and shine.
26 citations
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July 2007 in “Biochemical Pharmacology” This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that hair-type tissues in hedgehogs show higher enrichment of immune-related genes compared to spine-type tissues, suggesting that spines evolved to protect against injuries and infections.
8 citations
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November 2010 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that calcitriol protects keratinocytes from the cell detachment and apoptosis caused by captopril exposure.
38 citations
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November 2020 in “International journal of biochemistry & cell biology” This review discusses the biological roles and diagnostic significance of keratins in mammalian colon epithelial cells and reports no new clinical results.
11 citations
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October 2020 in “PLoS ONE” This study found that scalp cooling markedly reduces cellular uptake of anthracycline drugs in human keratinocytes, partially explaining its protective effect against chemotherapy-induced cytotoxicity.
1 citations
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December 2020 The skin is the body's largest organ, with layers, cells, and structures that protect and support it.
May 2023 in “International journal of molecular sciences” This study investigated the role of the ABCA4 gene in human keratinocytes and hair follicle stem cells and found that silencing the ABCA4 gene increases the harmful effects of all-trans-retinal on hair follicle stem cells.
November 2022 in “Journal of Investigative Dermatology” This study found that apocynin restored collagen production, reduced DNA damage and senescence, and protected skin stem cells from aging in UVB-exposed human keratinocytes.
September 2017 in “Journal of Investigative Dermatology” This study found that mackerel fermented fish oil protected human keratinocyte cells from UVB-induced oxidative stress by scavenging free radicals and reducing cellular damage.
January 2025 in “Journal of Bioresource Management” This study found that inhibiting the ATR kinase with VE-822 impairs DNA repair capability in quiescent human keratinocytes exposed to solar-simulated UV radiation, suggesting ATR's critical role in facilitating effective DNA damage repair and cellular recovery under UV stress conditions.
This study found that in an ex vivo model simulating alopecia areata, the DHODH inhibitor farudodstat reduced T-cell proliferation and MHC protein expression in hair follicles, suggesting it may protect against immune privilege collapse without cytotoxic effects.
February 2021 in “Cermin Dunia Kedokteran” This review discusses the protective effects of vitamin D on skin aging and its role in hair growth, but reports no new clinical results.
October 2021 in “International Journal of Dermatology” This article poses the question of whether Janus kinase (JAK) inhibitors are beneficial for treating androgenic alopecia, but it does not provide results or conclusions from any study.
19 citations
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December 2006 in “Journal of Structural Biology” Type I and Type II keratin chains can form heterodimers despite sequence differences.
This study used an ex vivo human skin model to show that tropical conditions disrupt skin homeostasis, resulting in epidermal thickening and junctional flattening, and found that Kombucha tea extract may help preserve skin structure under such stress.
May 2014 in “Journal of The American Academy of Dermatology” The project aimed to understand how genetic test results affect patients' actions and feelings in dermatology.
4 citations
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June 2024 in “British Journal of Dermatology” This study found that treatment with EGFR inhibitors or mitogen-activated kinase inhibitors may compromise the immune privilege of human scalp hair follicles, suggesting new directions for managing drug-induced folliculitis.
1 citations
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January 2018 in “AUSTRALIAN JOURNAL OF BASIC AND APPLIED SCIENCES” In this study, the ethanol extract of Zapoteca portoricensis stem significantly reduced markers of testosterone-induced benign prostate hyperplasia in male albino rats without harming liver and kidney function.
January 2024 in “Indonesian Journal of Pharmaceutical Education” In this experimental laboratory study, three cream formulations containing 1% Caffeine Herbasome® were developed and evaluated for stability, homogeneity, pH, dispersion, and adhesion, with results showing satisfactory stability and suitable adhesion properties for skin application.
Folicrex may help with hair growth and health but lacks clinical evidence.
1 citations
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November 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews the digitization of historical issues of the Journal of Investigative Dermatology, highlighting the impact and citation durability of its 1970 publications; it reports no new clinical results.
20 citations
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January 2001 in “Journal of Cutaneous Laser Therapy” This study found that wound healing after CO(2) laser resurfacing is faster with occlusive dressings, as they enhance cell migration from hair follicles, compared to untreated skin, which showed delayed re-epithelialization.
May 2026 in “Journal of Health Sciences and Medicine” This study found that biotinoyl tripeptide-1-loaded solid lipid nanoparticles significantly improved thermal protection in hair, enhancing cuticle integrity and resistance to heat damage, compared to control samples.
April 2023 in “Journal of Investigative Dermatology” This study found that local injection of anti-HSV sera in mice provided long-term protection against zoster-like skin lesions and sweating disturbances following an HSV-1 challenge.
August 2015 in “Free Radical Biology and Medicine” Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
January 2005 in “ScholarSpace (University of Hawaii at Manoa)” This project reports that Vitex rotundifolia may have cancer chemotherapeutic potential due to its ability to inhibit MAP kinase phosphorylation, suggesting further investigation into its active constituents.
January 2024 in “AIP conference proceedings” This review reports that medicinal plant-based hydrogel films may enhance diabetic wound healing by increasing growth factor expression involved in tissue repair and regeneration, suggesting their potential in future diabetic wound dressing development.
34 citations
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August 2011 in “Journal of Natural Medicines” This study found that Puerariae Flos extract inhibited testosterone 5α-reductase and promoted hair growth in mouse models, suggesting its potential use for treating androgenic alopecia.