2 citations
,
January 2020 in “Methods in molecular biology” This study describes a protocol for generating hair follicle germ-like organoids from human skin cells, which may aid in alopecia drug discovery and understanding hair follicle regeneration.
13 citations
,
December 2012 in “Frontiers in bioscience” This review discusses the potential role of vitamin D deficiency in cardiovascular and renal diseases and suggests that supplemental vitamin D could benefit cardiovascular outcomes, especially in African American and postmenopausal women; it reports no new clinical findings.
13 citations
,
August 2021 in “Journal of Cosmetic Dermatology” This study found that Camellia sinensis (tea) extracts may protect hair from UV-induced damage and color change, with efficacy linked to higher concentrations of key compounds like catechins.
4 citations
,
January 2020 in “Elsevier eBooks” This review discusses the protective and reparative properties of chitin nanofibrils on hair structure and reports no clinical results; the authors suggest chitin-based products may aid in hair regrowth.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a partially automated protocol utilizing hair follicles for DNA extraction in marmosets, achieving reliable whole genome sequencing with low chimerism, offering an efficient alternative to blood for genetic studies in non-human primates.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers developed a non-invasive, partially automated protocol for extracting DNA from marmoset hair follicles, resulting in high-quality whole genome sequencing with low chimerism levels, making it a reliable method compared to blood DNA sequencing in these primates.
October 2021 in “Nepal journal of dermatology, venereology & leprology” This review discusses the diverse roles and potential skin health benefits of melatonin, highlighting its anti-inflammatory, antioxidant, and protective effects but reports no new clinical results.
April 2018 in “Journal of Investigative Dermatology” This study found that the PPAR-γ modulator AGED can reverse epithelial-mesenchymal transition in hair follicles affected by lichen planopilaris ex vivo, suggesting potential for treating scarring alopecias.
April 2016 in “JAMA Dermatology” This commentary highlights the importance of additional sun protection for individuals with alopecia, noting that common headwear like baseball caps may provide insufficient photoprotection for the scalp.
23 citations
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March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that extracellular ATP released from UVB-irradiated keratinocytes promotes melanin production through the P2X7 receptor, indicating a role for ATP-P2X7 signaling in UV-induced melanogenesis.
113 citations
,
June 2015 in “Stem Cell Research & Therapy” This study found that activation or inhibition of Wnt/β-catenin and Notch signaling pathways in rats can alter wound healing, possibly by affecting epidermal stem cell activity and keratinocyte behavior.
42 citations
,
February 2014 in “Stem Cells and Development” This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.
23 citations
,
December 2006 in “Evaluation and Program Planning” This article presents a model for evaluating public R&D that emphasizes measuring capacity-based metrics over traditional outcome-based metrics, using the concept of a Knowledge Value Collective.
4 citations
,
March 2019 in “Experimental Biology and Medicine” This study found that exposure to 50 Hz electromagnetic fields enhanced hair regrowth in mice by increasing stem cell proliferation and keratinocyte growth factor expression, suggesting potential benefits for hair loss treatment.
3 citations
,
May 2024 in “Amino Acids” This review identifies cysteine's central role in hair growth and its potential impact on Alopecia Areata's pathogenesis, suggesting examination of cysteine metabolism might clarify the disease's underlying mechanisms and lead to new treatments.
2 citations
,
May 2023 in “Plants” In this study, Allium hookeri extract increased viability and size of dermal papilla cell spheroids and reduced oxidative stress effects, potentially promoting hair growth by regulating specific protein signaling pathways in human cells.
This study identified a genetic locus associated with rhabdomyosarcoma susceptibility in mice and found that specific differentiation markers are linked to the regression of basal cell carcinoma.
101 citations
,
October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” This review reports on the dual aspect of fullerene in skincare, highlighting its beneficial antioxidant properties as well as potential toxicity and skin cell reactions, while identifying areas for future research.
7 citations
,
October 2019 in “Frontiers in bioengineering and biotechnology” This study found that pretreatment with KP-Cryst fusion proteins effectively protected Asian and Caucasian virgin hair from thermal damage by maintaining higher water content and preventing structural changes during heat application.
222 citations
,
January 2005 in “Endocrine journal” This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
165 citations
,
January 2008 in “Journal of biomaterials science. Polymer ed.” This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.
52 citations
,
September 2018 in “International Journal of Molecular Sciences” This review highlights the potential of ginseng and its metabolites in preventing hair loss, detailing their hair growth-promoting effects observed in numerous preclinical studies, and emphasizing the underlying mechanisms involved.
45 citations
,
September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that deleting β-catenin in epidermis-specific VDR knockout mice did not prevent UVB-induced skin tumors, indicating β-catenin does not compensate for VDR's role in tumor suppression.
33 citations
,
March 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.
15 citations
,
August 2020 in “Analytical chemistry” This study observed that lipids in human hair accumulate in specific areas and do not significantly impact water permeability, highlighting the utility of AFMIR for studying complex biomaterials.
7 citations
,
May 2024 in “Tissue Barriers” The researchers reported that components of keratinocytes influence the formation and differentiation of the stratum corneum, the epidermis's most specialized layer.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study formulated and evaluated a herbal shampoo using rice water and willow bark extract, finding that this combination supports healthy hair and scalp care by providing effective cleansing, nourishment, and improved manageability without the harsh effects of synthetic ingredients.
April 2026 in “Aesthetic Cosmetology and Medicine” This literature review examines current anti-aging therapies, focusing on innovative genetic cosmeceuticals enhanced by nanotechnology, which offer targeted and minimally invasive treatment options by effectively delivering anti-ageing genetic elements to skin cells and potentially improving skin health through reduced oxidative stress.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the formulation and evaluation of herbal hair serums, highlighting the use of natural ingredients like fenugreek, hibiscus, and kalonji, which are claimed to improve hair strength and scalp health.