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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Hair follicle stem cells help skin heal and grow during stretching.

Histone modification is key in treating chronic inflammatory skin diseases.

Taking vitamin D might improve life for MS patients and reduce skin side effects from alemtuzumab treatment.

Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.

Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.

miR-203a-3p helps hair follicle stem cells become specialized by targeting Smad1.

IL-3 worsens lupus nephritis and blocking it improves kidney health.

COVID-19 can cause hair loss, and treatments like PRP and stem cells might help.

Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.

Adipose-derived stem cells may help with hair loss, but more research is needed.

Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.

Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.

Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.