4 citations
,
March 2016 in “Dermatologic Surgery” PRP treatment increased hair density, especially in men and younger patients with AGA.
41 citations
,
October 2011 in “Clinical and Experimental Dermatology” This meta-analysis suggests that the G allele of AR StuI polymorphism might be a potential risk factor for AGA, particularly in white populations.
November 2025 in “Journal of Investigative Dermatology” A new genetic mutation causing Xeroderma Pigmentosum was found in an 8-year-old girl, affecting her DNA repair.
8 citations
,
January 2012 in “General and Comparative Endocrinology” 5α-Reductase helps regulate hormone action in toad testes, especially during breeding season.
This study reported the genotypic and allelic frequencies of seven SNPs associated with androgenetic alopecia in Mexican individuals, highlighting significant differences in one SNP between cases and controls in Western Mexico.
28 citations
,
March 2010 in “British Journal of Dermatology” This abstract contains only supplementary material information and reports no new research findings.
7 citations
,
July 2014 in “Reproductive Biomedicine Online” This study found that, among fertile egg donors, the AR gene CAG polymorphism was associated with differences in antral follicle count but did not impact ovarian response to gonadotrophins.
May 2023 in “Reactions Weekly” January 2013 in “Reactions Weekly”
9 citations
,
March 2009 in “Psychoneuroendocrinology” This study found that variations in the androgen receptor gene influenced memory function in women, with GGN repeat polymorphisms significantly affecting logical memory performance only in females.
January 2025 in “Buleria (Universidad de León)”
In a randomized, double-blinded, placebo-controlled clinical trial, this study found that the botanical-based compound ALRV5XR significantly increased hair regrowth in women with androgenetic alopecia or telogen effluvium, with no adverse events reported.
2 citations
,
July 2015 in “Journal of Cosmetic Dermatology” This study did not find any correlation or linkage disequilibrium between androgen receptor gene CAG/GGC haplotypes and androgenetic alopecia in Mexican brothers.
1 citations
,
May 2017 in “Hair transplant forum international” This paper discusses the recent online debate over the use of PRP in hair restoration but provides no new findings.
5 citations
,
March 2005 in “Journal of The American Academy of Dermatology” December 2025 in “ILDS-DEV” January 2025 in “Regenerative Biomaterials” This study found that a microneedle patch with recombinant collagen XVII significantly improved hair coverage, follicle density, and angiogenesis in an androgenic alopecia mouse model, showing potential as a novel therapeutic strategy alongside established treatments like minoxidil.
8 citations
,
March 2020 in “Frontiers in Cell and Developmental Biology” This study developed a DPC cell line by introducing mutant CDK4, Cyclin D1, and TERT, making it a promising tool to study downstream signaling pathways activated by testosterone in androgenetic alopecia.
32 citations
,
November 2020 in “UNC Libraries” This study identified a mutation in the steroid-binding domain of the androgen receptor gene associated with complete androgen insensitivity syndrome, impairing male sexual development due to altered androgen receptor protein function.
23 citations
,
January 2014 in “International Journal of Biological Sciences” This study found that African American men with prostate cancer have higher rates of somatic and germline androgen receptor mutations than Caucasian American men, which may contribute to ethnic differences in disease progression and outcomes.
29 citations
,
July 2013 in “The Journal of Sexual Medicine” This review discusses the potential role of androgen receptor CAG repeat polymorphism testing in hypogonadism management for both sexes, but its clinical utility remains unclear and requires further investigation.
January 2006 in “Chinese Journal of Dermatology” This study suggests that polymorphisms in the androgen receptor gene's GGC repeat and the combined CAG-GGC triplet repeats are associated with androgenetic alopecia among Han men in Eastern China.
This study tested a novel cryo-carboxy dispensing device for treating androgenetic alopecia in six volunteers and found an unexpectedly rapid and positive response, with significant hair regrowth observed by day 90, prompting early conclusion of the trial.
October 2022 in “Journal of Drugs in Dermatology” This study observed that both PRP and 1550 nm fractional erbium-glass laser improved AGA, with greater hair density in patients receiving the combination therapy and no side effects reported.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research outlines an innovative bioregeneration chamber aimed at significantly extending human lifespan and enhancing health maintenance by treating the body as a thermodynamic system, potentially enabling an average lifespan of 130 to 150 years in an advanced therapeutic setting.
1 citations
,
November 2006 in “Medicina de Familia SEMERGEN”
30 citations
,
July 2019 in “Endocrinology” This review discusses how the HSD3B1(1245C) genotype may impact androgen physiology and the progression of castration-resistant prostate cancer, and does not report new experimental results.
3 citations
,
January 2008 in “Endocrine journal” In this case report, the authors describe a partial androgen insensitivity syndrome patient with a novel AR gene mutation, highlighting challenges in gender assignment decisions for infants with partial AIS.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study presents the design of an autonomous bioregeneration chamber that aims to extend human lifespan to 130-150 years by optimizing biological and environmental conditions, suggesting that a longer healthspan is possible through technological, nutritional, and socio-economic interventions.
January 2026 in “Journal of Dermatological Treatment” This source discusses a Phase 2 trial by Hu et al. that evaluated the efficacy of topical GT20029 compared to a placebo, though the abstract does not provide specific results.