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Middle-aged women in Iran are most affected by primary cicatricial alopecia, especially discoid lupus erythematous.

A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.

Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.

Early and aggressive treatment of scarring alopecia is important to prevent further hair follicle damage.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.

Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.

Dermatologists diagnose and manage melanoma more effectively than general practitioners.

Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

Iron deficiency anemia can cause itching, which often improves with iron supplements.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.