Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that proper levels of retinoic acid, controlled by the enzyme Cyp26b1, are essential for normal hair follicle development and morphogenesis in mice.

In this case report, a 21-year-old male was observed to have primary essential cutis verticis gyrata, a condition characterized by the excessive formation of scalp folds resembling cerebral gyri, without any additional comorbidities.

This review discusses common skin conditions in primary care settings and provides guidance on differential diagnoses and selecting appropriate topical treatments, but it reports no new clinical results.

In this study, researchers developed a rapid platform using primary human lung tissues to identify SARS-CoV-2 targets and test antiviral compounds, achieving highly reproducible results across viral variants.

This case report details a rare instance of primary adrenal insufficiency as a manifestation of antiphospholipid syndrome, with the patient successfully managed through glucocorticoids, warfarin, and hydroxychloroquine.

This study found that a spontaneous deletion in the Dsg3 gene of mice leads to hypomorphic desmoglein 3 expression, resulting in severe immunodeficiency, cyclic hair loss, and wasting disease, without causing the blistering typical of pemphigus vulgaris.

This article reviews common causes of hair loss and hair excess and discusses their management in primary care settings, but it reports no new clinical results.

This case report describes a 47-year-old woman with dilated cardiomyopathy as the first sign of primary antiphospholipid syndrome, highlighting the need for APS screening in similar patient presentations.

This study observed that adult Netherton syndrome patients showed a range of normal to diminished immune responses to polysaccharide, conjugate, and mRNA-based vaccines, with responses generally overlapping those of healthy controls, suggesting no consistent B- or T-cell immunodeficiency in this population.

This case report highlights the challenge of diagnosing systemic lupus erythematosus in males and antinuclear antibody-negative patients, emphasizing the need for primary care doctors to maintain a high suspicion of the condition.

This review highlights the demonstrated efficacy and growing use of upadacitinib for cutaneous disorders, emphasizing its cost-effectiveness and recent availability in India compared to other biologics and small-molecule therapies, rather than providing new primary data.

In this case report, a rare occurrence of Paraneoplastic Dermatomyositis following breast cancer was observed in a 50-year-old woman, indicating the importance of multidisciplinary approaches for identifying underlying malignancies when Dermatomyositis presents as a primary symptom.

This review discusses current anti-inflammatory treatment options for calcium pyrophosphate crystal deposition disease (CPPD) and highlights the lack of crystal-targeted therapies, emphasizing the need for more research to guide treatment.

This case study suggests that treatment with Pil-Food, intended for hair loss prevention, may have triggered postinfantile giant cell hepatitis with autoimmune characteristics, which showed a rapid and effective response to corticosteroid therapy.

This study demonstrated that implanting μm-scale full-thickness columns of human skin tissue into immunodeficient mice restored key features of normal human skin, suggesting potential for human wound repair with minimal donor site morbidity.

The document discusses various diseases of the outer ear, categorized by symptoms like redness, crusts, bumps, pus-filled lesions, lumps, ulcers, and hair loss.

In this case report, the authors describe a female dog with alopecia in the neck and ear region, affected by dermatophytosis caused by the zoophilic fungus Microsporum canis, highlighting its zoonotic potential and prevalence in certain climates.

This review outlines the advancements in organ and tissue transplantation since the discovery of the human MHC and reports no new clinical results.

This review summarizes existing knowledge on the role of FOXN1 as a key regulator of thymic epithelial cell lineage and function, reporting no new experimental results.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

This case report describes a 10-month-old boy with VACTERL association and athymia who developed Omenn syndrome, highlighting the complex overlap of these conditions and the challenging clinical course due to profound T-cell immunodeficiency.

This review discusses the use of recombinant cytokines as therapeutic agents in clinical settings and describes the range of cutaneous complications associated with their use, including both minor and severe skin reactions.

This study found that thymus transplantation in infants with FOXN1 deficiency led to T-cell reconstitution and functional immunity, resolving serious infections and cytopenias.

This review provides practical guidelines for managing psychodermatologic disorders and concludes that psychopharmacologic agents offer a useful option for treatment, considering the underlying psychopathologic condition.

This study found that supplementing soybean oil significantly increased the production of the cyclosporine A derivative [(4'-OH)MeLeu]4-CsA by 55.6%, offering potential enhancements for its clinical application.

This review highlights the diverse cutaneous manifestations in immunocompromised patients, emphasizing the importance of early recognition for improved patient prognosis.

This review examines the causes, symptoms, diagnosis, and treatment of dermatophytosis (ringworm) in dogs and cats, highlighting the role of Microsporum canis and the public health implications of zoophilic dermatophytes, affecting roughly 20-25% of the global population.

This study evaluated the long-term effects of combining autologous platelet-rich stroma injection with transanal advancement flap repair for cryptoglandular transsphincteric fistulas and found that it resulted in primary clinical closure and radiological healing in a high percentage of patients, with low recurrence rates.

This paper reviews delusional infestation, its characteristics, and treatment options, highlighting a case study of a man with a strong belief in a nonexistent lice infestation and recommending low-dose antipsychotics for primary cases.

Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.