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The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Oestrogens are key for bone growth during puberty in both boys and girls.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Latanoprost can make eyelashes longer, thicker, and darker.

Blocking JAK-STAT signaling can lead to hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

The document concludes that proper diagnosis and a combination of medical, hair-care, and surgical treatments are important for managing alopecia in black women.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

An mFG score of 5 or more indicates above-normal hair growth in Southern Chinese women.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.