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Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.

Red light therapy is safe and effectively increases hair growth in women with hair loss.

Despite progress, better treatments and understanding are needed for the high rates of long-term issues and deaths linked to eating disorders.

PDRN helps repair tissue and improve wound healing with a high safety profile.

The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Minoxidil foam enters hair follicles and skin for hair growth.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

The document concludes that good cosmetic outcomes in hair transplantation depend on the surgeon's artistic skill and careful planning.