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Dermal EZH2 controls skin cell development and hair growth in mice.

Polycomb Repressive Complex 2 is not needed for hair regeneration.

Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

Dermal EZH2 controls skin cell growth and differentiation in mice.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.

Epigenetic changes are crucial for hair follicle stem cells to function properly.

The research found genes that may protect certain scalp cells from hair loss.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Researchers identified specific genes that are important for mouse skin cell development and healing.

The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

Epigenetic mechanisms control skin development by regulating gene expression.

Enzymes called PADIs play a key role in hair growth and loss.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Trazodone might help reverse post finasteride syndrome.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Hoxc genes control hair growth through Wnt signaling.