research Peroxisome Proliferator Activated Receptor-Gamma Tissue Expression and Gene Polymorphism in Alopecia Areata in an Egyptian Sample
PPAR-γ may be a key target for treating alopecia areata and other skin conditions.
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30 / 731 results research Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth
PPAR alpha may help in hair growth and could be a target for treatment.
research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ
Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
research PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia
PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
research PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
research Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin
PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
research Long Non-Coding RNA AL136131.3 Inhibits Hair Growth Through Mediating PPARγ in Androgenetic Alopecia
A specific RNA molecule blocks hair growth by affecting a protein related to hair loss conditions.
research Loss of Adipocyte Phospholipase Gene PLAAT3 Causes Lipodystrophy and Insulin Resistance Due to Inactivated Arachidonic Acid-Mediated PPARγ Signaling
Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.
research PPAR-γ Modulation as a Novel Therapeutic Strategy for Scarring Alopecia
A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.
research The PPAR-γ Modulator, N-Acetyl-GED, Protects From Epithelial-Mesenchymal Transition in Human Hair Follicles: Potential Relevance for Scarring Alopecia
N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
research Early Skin Seeding Regulatory T Cells Modulate PPARγ-Dependent Skin Pigmentation
Early regulatory T cells are crucial for normal skin pigmentation.
research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research How to Diagnose a Lipodystrophy Syndrome
The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
research Lichen Planopilaris and Frontal Fibrosing Alopecia: Review and Update of Diagnostic and Therapeutic Features
The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.
research Adipose and Hair Function: An Apparent Connection
Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
research Hot Stuff: Thermal Imaging Aids in Cellulitis Diagnosis
The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.
research Treatment of Cultured Sebocytes with an EGFR Inhibitor Does Not Lead to Significant Upregulation of Inflammatory Biomarkers
Blocking EGFR in skin cells doesn't majorly increase inflammation markers.
research Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages
Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.
research Cicatricial Alopecia: What's New in Etiology?
Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
research Dialogues in Dermatology: Highlights from 2011
2011 dermatology discussions highlighted stem cell hair treatments, new lichen planopilaris therapies, skin side effects from cancer drugs, emerging allergens, and the link between food allergies and skin issues.
research PPARγ Signaling Modulation Protects From Hair Follicle Bulge Stem Cell Damage and Cyclophosphamide-Induced Hair Follicle Cytotoxicity
PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.
research Intradermal Adipocytes Mediate Fibroblast Recruitment During Skin Wound Healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research Influence of Substance P on Cultured Sebocytes
Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
research Primary Cicatricial Alopecia: Recent Advances in Understanding and Management
New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
research Cicatricial Alopecia Symposium 2011: Lipids, Inflammation, and Stem Cells
The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.
research Distinct Mechanisms for Sebaceous Gland Self-Renewal and Regeneration Provide Durability in Response to Injury
Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
research Cicatricial Alopecia: Early Diagnosis and Treatment Strategies
Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.