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Eating fewer calories may slow skin aging and improve skin health through various biological changes.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Caffeine can protect scalp hair follicles from damage caused by UV radiation.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.

RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

A new treatment using AGED to modulate PPAR-γ shows promise for treating scarring hair loss by protecting and repairing hair follicle cells.

N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.

Loss of Rap1 protein speeds up heart aging in mice.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Melatonin improved mental health and metabolism in women with PCOS.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

The document concludes that more research is needed to find effective treatments for Lichen planopilaris and Frontal fibrosing alopecia.

Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.

The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.

Early diagnosis and aggressive treatment are crucial for Cicatricial Alopecia, and treatment effectiveness varies among patients.

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.