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      Molecular Mechanisms of Androgenetic Alopecia

      research Molecular mechanisms of androgenetic alopecia

      229 citations , August 2002 in “Experimental Gerontology”
      This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.
      Melatonin

      research MELATONIN

      220 citations , August 1988 in “Clinical endocrinology”
      This review provides a comprehensive overview of melatonin's physiological roles, effects, and clinical implications, but it does not present new experimental findings.
      The Rotterdam Study: 2010 Objectives and Design Update

      research The Rotterdam Study: 2010 objectives and design update

      219 citations , September 2009 in “European journal of epidemiology”
      This article discusses the rationale, design, major findings, and updated objectives and methods of the ongoing Rotterdam Study on various diseases, without reporting new research results.
      Hair Follicle Differentiation And Regulation

      research Hair follicle differentiation and regulation.

      199 citations , January 2004 in “The International Journal of Developmental Biology”
      This review discusses advances in understanding hair and hair follicle structure, gene expression, and molecular signals in hair formation, without reporting new clinical findings.
      Effects of Visible Light on the Skin

      research Effects of Visible Light on the Skin

      195 citations , January 2008 in “Photochemistry and Photobiology”
      This review discusses the effects of visible light on human skin, highlighting its role in pigmentation, thermal damage, and the treatment of several skin conditions, while noting limited sunscreen protection against it; no new clinical results are reported.
      COVID-19 and Sex Differences: Mechanisms and Biomarkers

      research COVID-19 and Sex Differences

      185 citations , August 2020 in “Mayo Clinic Proceedings”
      This review discusses biological sex differences in COVID-19 outcomes and reports no new clinical results; it identifies a need for studies to clarify how sex influences disease progression.
      Phenotypic Variation in Biotinidase Deficiency

      research Phenotypic variation in biotinidase deficiency

      184 citations , August 1983 in “˜The œjournal of pediatrics/˜The œJournal of pediatrics”
      In this study, biotinidase deficiency in children usually presented with neurological or skin symptoms, while metabolic ketoacidosis and organic aciduria appeared later.
      Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions

      178 citations , August 2016 in “Advances in wound care”
      This article discusses advancements in understanding how skin stem cells and fibroblasts contribute to scar formation, highlighting current and potential therapies aimed at preventing or reducing scarring, yet notes that effective treatments without significant side effects are still lacking.
      Androgenetic Alopecia: Pathogenesis and Potential for Therapy

      research Androgenetic alopecia: pathogenesis and potential for therapy

      174 citations , November 2002 in “Expert Reviews in Molecular Medicine”
      This review discusses the genetic factors contributing to androgenetic alopecia and highlights the potential for developing more effective therapies based on recent discoveries, but reports no new clinical results.
      Cutaneous Complications of Chemotherapeutic Agents

      research Cutaneous complications of chemotherapeutic agents

      172 citations , November 1983 in “Journal of The American Academy of Dermatology”
      This article discusses the cutaneous side effects of various chemotherapeutic agents but reports no new clinical results; the authors emphasize the importance of dermatologists recognizing drug-induced skin reactions to better patient care.
      Wound Healing and the Use of Medicinal Plants

      research Wound Healing and the Use of Medicinal Plants

      170 citations , September 2019 in “Evidence-based Complementary and Alternative Medicine”
      This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
      Prostaglandin-Induced Hair Growth

      research Prostaglandin-Induced Hair Growth

      162 citations , August 2002 in “Survey of Ophthalmology”
      This study found that latanoprost induces significant growth and pigmentation of lashes and ancillary hairs, with effects mirroring both brief and chronic treatments observed in patients and animal models.
      Androgens and Human Hair Growth

      research Androgens and human hair growth

      157 citations , April 1994 in “Clinical endocrinology”
      Androgens can cause hair growth in some areas and hair loss on the scalp.
      Androgenetic Alopecia: A Review

      research Androgenetic alopecia: a review

      153 citations , March 2017 in “Endocrine”
      This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
      Caffeine’s Mechanisms of Action and Its Cosmetic Use

      research Caffeine’s Mechanisms of Action and Its Cosmetic Use

      153 citations , October 2012 in “Skin Pharmacology and Physiology”
      This review discusses the use of caffeine in cosmetics for its fat-reducing, antioxidant, and hair growth properties, but reports no new research findings.
      Theoretical Considerations in Laser Hair Removal

      research Theoretical considerations in laser hair removal

      150 citations , April 1999 in “Dermatologic Clinics”
      This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.
      WNT Signaling in Disease

      research WNT Signaling in Disease

      144 citations , August 2019 in “Cells”
      This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
      Transfollicular Drug Delivery: Is It a Reality?

      research Transfollicular drug delivery—Is it a reality?

      141 citations , November 2005 in “International journal of pharmaceutics”
      This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.
      Alopecia Areata: Pathogenesis And Treatment

      research Alopecia areata: Pathogenesis and treatment

      122 citations , November 1984 in “Journal of the American Academy of Dermatology”
      This review discusses the potential autoimmune pathogenesis and various contributing factors of alopecia areata, noting that current treatments remain palliative while emerging therapies offer new hope for extensive cases.