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Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.

Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

New therapies are being developed that target integrin pathways to treat various diseases.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.

BMP signaling is essential for the development of touch domes.

Low selenium levels can extend lifespan but worsen health issues.

Testosterone may influence COVID-19 severity and outcomes.

Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.

Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.

Some COVID-19 patients lose hair, with the most common type linked to male hormones and possibly increasing the risk of severe illness.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.

There is a significant need for better-validated quality of life tools in dermatology.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

Adding a second method to PROTACs could improve cancer treatment.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

FGF21 can help reduce skin inflammation caused by C. acnes.

MG53 helps reduce skin damage caused by nitrogen mustard.