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This policy brief highlights that post-drug syndromes remain under-recognized in pharmacovigilance, leading to inadequate risk assessments and patient care. It identifies systemic failures in current frameworks and recommends actions to improve long-term drug safety monitoring and education, affecting public health outcomes significantly.

In this study, curcumin was efficiently loaded into PS–PAA nanoparticles at the formation stage, showing even distribution at low concentrations and good biocompatibility with human skin fibroblasts.

This study found that 8% Panax notoginseng saponins may promote hair follicle growth in C57BL/6J mice, potentially through the Wnt/β-catenin signaling pathway.

In this study, Paljeong-san pharmacopuncture reduced dihydrotestosterone levels and inhibited prostate tissue proliferation in a rat model of benign prostatic hyperplasia.

Pallister-Killian Syndrome is a complex genetic disorder requiring coordinated care and genetic counseling.

This study found that serum PSA levels and %fPSA have limited diagnostic capability in distinguishing prostate cancer, suggesting a need for new, more specific and sensitive markers.

In this study, black cumin oil-based nanostructured lipid carriers enhanced the delivery and effectiveness of fluticasone for psoriasis in a mouse model, improving skin targeting, inflammation reduction, and permeability compared to standard cream.

This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.

This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.

Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.

This study found that videodermoscopy can help diagnose nailbed psoriasis by revealing distinctive hyponychial capillary patterns, which correlated with disease severity and response to treatment.

This review examines the potential of Parquetina nigrescens for managing Polyendocrine Metabolic Ovarian Syndrome, emphasizing its pharmacological activities and highlighting its promise as an affordable complementary therapy.

Polygenic Score can help predict severe psoriasis and psoriatic arthritis.

Clear definitions and strategies are needed to manage long-term COVID-19 symptoms effectively.

In an animal study, this research explored the use of a self-therapeutic nanoparticle for treating psoriasis in mice, finding that it could prevent and treat psoriatic symptoms as effectively as standard therapies without causing side effects like hair loss and skin wrinkling.

This study found that while the combination of oral propranolol and intradermal injections in guinea pigs led to psoriasiform changes, it did not fully mimic psoriasis.

In this study, combining transcranial electrical stimulation with bisphosphonate therapy in patients with postmenopausal osteoporosis resulted in a protective effect on bone collagen synthesis, as indicated by higher P1NP levels over 12 months, compared to bisphosphonates alone.

This study identified 24 independent genetic variations and 127 unique genes associated with nociplastic pain, suggesting it is a complex, heritable trait with links to various cognitive and metabolic pathways.

This study observed that adult Netherton syndrome patients showed a range of normal to diminished immune responses to polysaccharide, conjugate, and mRNA-based vaccines, with responses generally overlapping those of healthy controls, suggesting no consistent B- or T-cell immunodeficiency in this population.

This case report describes the histopathological features of nevus psiloliparus in an 11-year-old girl, noting "shadow" follicular units with loosely arranged collagen and reduced elastic fibers.

In this study, combining Polynucleotides High Purification Technology with hyaluronic acid significantly reduced atrophic post-acne scar areas and improved Goodman-Baron scores in a majority of treated patients over six months, reaffirming the approach's beneficial effects in a real-world outpatient setting.

This case study highlights the unique occurrence of Papillon-Lefévre syndrome in two siblings from a consanguineous family, emphasizing the potential role of genetic factors in the disease's development.

This study found that a hair conditioner using peptides from Pneumatophorus japonicus heads improved damaged hair's structure, gloss, and smoothness more effectively than a commercial wheat protein conditioner by increasing amino acid content and interacting with hair keratin.

Pityriasis rubra pilaris is a rare skin disorder with reddish-orange patches and thickened skin, needing better treatment understanding.

This study found that a history of smoking significantly predicted a more refractory course of palmoplantar pustulosis, with associated comorbidities often including hypertension, type 2 diabetes mellitus, and thyroid diseases.

This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.

This review discusses newly identified non-Edg family lysophosphatidic acid receptors, detailing their roles in vascular development, platelet activation, and hair growth, and reports no clinical results.

This study found that incorporating a block copolymer significantly alters the size and morphology of niosome drug delivery systems made of non-ionic surfactants and cholesterol, affecting their stability.

Nephronectin is linked to worse outcomes in breast cancer and helps cancer spread.

This study found that p2y5 functions as a novel LPA receptor involved in the G13-Rho signaling pathway, with implications for human hair growth, and proposes renaming it to LPA6.