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The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.

Tongue cancer cells show more plectin-1 than non-cancer cells, but both have similar levels of trichohyalin.

A patient with a new PLEC gene mutation showed symptoms of both muscular dystrophy and myasthenia gravis, which improved with steroid treatment.

Neutrophils quickly respond to skin injury.

A new mutation in the PLEC gene causes a rare condition with skin blistering, muscle weakness, and hair loss.

A rare gene mutation causes skin fragility and itching without affecting hair or nails.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

The document suggests that certain protein deficiencies and scalp blistering in Epidermolysis Bullosa may cause hair loss.

Hair loss in autoimmune blistering skin diseases varies and may regrow with disease control.

Found different proteins in balding and non-balding cells, giving insight into hair loss causes.

Collagen XVII is important for skin aging and wound healing.

Terbinafine can cause hair loss.

Alopecia in patients with epidermolysis bullosa varies in severity and is often caused by skin blistering or trauma.

Cyclosporin doesn't stop hair loss.

K6hf is a unique protein found only in a specific layer of hair follicles.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Non-immune factors play a significant role in alopecia areata.

Low-level laser therapy improves hair growth and dermal papilla cell function.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.

The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.