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Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Androgens can both increase and decrease hair growth in different parts of the body.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Finasteride effectively blocks enzyme causing male pattern baldness.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.