research A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
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30-60 / 1000+ results research Comparison of Efficacy of Platelet-Rich Plasma Therapy With or Without Topical 5% Minoxidil in Male-Type Baldness: A Randomized, Double-Blind Placebo Control Trial
PRP combined with minoxidil is the most effective and safe treatment for male pattern baldness.
research Double-Blind Randomized Placebo-Controlled Study of the Efficacy and Safety of Hair Loss Prevention Shampoo Containing Salicylic Acid, Panthenol, and Niacinamide in Alopecia Patients
The shampoo with salicylic acid, panthenol, and niacinamide is effective and safe for preventing hair loss in people with alopecia.
research Blinding in Placebo-Controlled Trials
The conclusion is that maintaining blinding in clinical trials is crucial for reliable results.
research An Oral French Maritime Pine Bark Extract Improves Hair Density in Menopausal Women: A Randomized, Placebo-Controlled, Double-Blind Intervention Study
French maritime pine bark extract significantly increased hair density in menopausal women.
research Blinding in Placebo-Controlled Trials
The conclusion suggests that the zinc lozenge study is valid despite imperfect blinding, as many participants could not correctly identify their lozenge type.
research Pooled Safety and Tolerability Data from Four Placebo-Controlled Teriflunomide Studies and Extensions
Teriflunomide is safe and tolerable for treating relapsing-remitting multiple sclerosis, with manageable side effects.
research Low-Dose IL-2 for Treating Moderate to Severe Alopecia Areata: A 52-Week Multicenter Prospective Placebo-Controlled Study Assessing Its Impact on T Regulatory Cell and NK Cell Populations
The study's results on the effectiveness of low-dose IL-2 for alopecia areata and its impact on immune cells were not provided.
research Platelet-Rich Plasma for the Treatment of Erectile Dysfunction: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
PRP is safe but not more effective than a placebo for treating mild to moderate erectile dysfunction.
research Final Results of a Randomized, Placebo-Controlled, Two-Arm, Parallel Clinical Trial of Proxalutamide for Hospitalized COVID-19 Patients: A Multiregional, Joint Analysis of the Proxa-Rescue AndroCoV Trial
Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.
research Evaluation of Gel Formulation of Trigonella Foenum-Graecum Seed on Prevention of Trichoptilosis in Randomized Placebo-Controlled Clinical Trial
Fenugreek gel significantly reduces split ends and improves hair health.
research Efficacy and Safety of L-Cystine Associated or Not to a Natural Keratin (Kera-Diet) Hydrolysate on Hair and Nails: Randomized, Placebo-Controlled, Clinical Trial on Healthy Females
L-Cystine and L-Cystine with Kera-Diet® safely improved hair and nail quality in healthy women.
research Comparison Between Topical Cetirizine With Minoxidil Versus Topical Placebo With Minoxidil In Female Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Study
Adding cetirizine to minoxidil improves hair growth and thickness in women with androgenetic alopecia.
research A Phase IIA Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of the Selective Androgen Receptor Modulator (SARM), MK-0773 in Female Participants with Sarcopenia
MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
research Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia
PRP shows potential for treating female hair loss, but more research needed.
research Cyclosporine for Moderate-to-Severe Alopecia Areata: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of Efficacy and Safety
Cyclosporine showed some improvement in alopecia areata but results were not statistically significant.
research Efficacy and Tolerability of Hairgain in Individuals with Hair Loss: A Placebo-Controlled, Double-Blind Study
Hairgain® significantly increased hair growth and was well-tolerated by individuals with hair loss.
research Capryloyl Glycine And Soy Isoflavonoids In Hypertrichosis: An Experimental And Placebo-Controlled Clinical Study
The study investigated a cream with 4% capryloyl glycine and 1% soy isoflavonoids for treating hypertrichosis on the forearms of 12 Caucasian female patients. The cream significantly reduced ornithine decarboxylase 1 (ODC1) activity by 35.1%. After four months, 91.7% of patients using the cream showed improvement, with 58.3% experiencing good efficacy and 41.7% moderate efficacy, while the placebo group showed no improvement. The cream was well-tolerated, with no adverse events and good cosmetic acceptability. The study concluded that the cream effectively reduced hair growth in the tested population, but recommended further trials with more participants to confirm these findings.
research Efficacy and Safety of Topical KX-826 in Male Subjects with Androgenetic Alopecia: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Study
KX-826 is safe and effectively increases hair count in men with hair loss.
research Evaluation of the Efficacy and Safety of Topical Procyanidin B2 and Placebo in the Treatment of Androgenetic Alopecia in Men: A Randomized, Double-Blind, Placebo-Controlled Study
Topical procyanidin B2 significantly increases hair count and is a safe treatment for male pattern baldness.
research Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial
Topical clobetasol is recommended over mycophenolate mofetil for treating Lichen Planopilaris due to better safety and patient satisfaction.
research Efficacy and Safety of a Dietary Supplement Containing a Lipid Co-Extract from Serenoa Repens and Pygeum Africanum for the Treatment of Androgenetic Alopecia in Women: Results of a Randomized, Double-Blind, Placebo-Controlled Clinical Trial
The supplement with Serenoa repens and Pygeum africanum significantly increased active hair growth and decreased rest phase hair in post-menopausal women with hair loss, with only mild digestive side effects.
research Skin Health Promoting Effects of a Proprietary Nutraceutical Ingredient (SesZen-Bio): A Placebo-Controlled, Double-Blind, and Randomized Clinical Study
The study investigated the effects of SesZen-BioTM, a 0.5% natural biotin supplement, on skin health in a double-blind, placebo-controlled trial involving adults aged 30-55 with mild skin aging. Results showed significant improvements in the treatment group, including a reduction in crow’s feet and fine lines by up to 48.14% and 51.17% respectively, enhanced skin tone, elasticity, and hydration, and a decrease in skin roughness. The placebo group showed no significant improvements. These findings suggest that SesZen-BioTM is effective in promoting skin health and combating signs of aging.
research Efficacy of an Oral Ageratum Conyzoides Formulation on Increasing Hair Growth and Decreasing Hair Loss in Males and Females: A Randomised Double-Blind Placebo-Controlled Study
Ageratum Conyzoides, when taken orally, can effectively reduce hair loss and improve hair growth.
research Dietary Supplement Increases Anagen Hair Rate in Women With Telogen Effluvium: Results of a Double-Blind, Placebo-Controlled Trial
The dietary supplement helped increase hair growth in women with hair loss.
research Efficacy of Postbiotics in a PRP-Like Cosmetic Product for the Treatment of Alopecia Areata: A Randomized Double-Blinded Parallel-Group Study
The PRP-like cosmetic product with postbiotics effectively treats hair loss in Alopecia areata.
research Double-Blind, Randomized, Placebo-Controlled Trial of a Cream Containing the Stryphnodendron Adstringens (Martius) Coville Bark Extract for Suppressing Terminal Hair Growth
The study evaluated the efficacy of a cream containing 6.0% Stryphnodendron adstringens bark extract for suppressing terminal hair growth in women with excessive hair. Conducted as a double-blind, randomized, placebo-controlled trial, the study found that 60.98% of subjects using the cream experienced significant benefits (P < 0.001), with the Ferriman-Gallwey score improving from 4 to 2, compared to 4 to 3 in the placebo group. The cream effectively reduced terminal hair growth and associated skin issues like hyperpigmentation, folliculitis, and acne, with no adverse events reported, suggesting it was a promising treatment for excessive terminal hair.
research A Spermidine-Based Nutritional Supplement Prolongs the Anagen Phase of Hair Follicles in Humans: A Randomized, Placebo-Controlled, Double-Blind Study
A spermidine-based supplement may help hair grow longer by keeping it in the growth phase.
research Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Ginger supplements helped reduce symptoms and improve metabolic health in hypothyroid patients.
research A Synbiotic Preparation (SIM01) for Post-Acute Covid-19 Syndrome in Hong Kong (Recovery): A Randomised, Double-Blind, Placebo-Controlled Trial
SIM01 significantly reduced post-COVID symptoms and is safe.