In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.
This study examined the molecular communication in psoriasis cells, highlighting unique immune cell interactions and identifying new features of the hair follicle cell-psoriasis axis. It suggests the potential for targeted therapies at the single-cell level to improve psoriasis treatment.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
This thesis found that desmoplakin mutations in cardiocutaneous syndrome are linked to dose-dependent disease severity and identified mechanisms by which KLHL24 mutations cause cardiomyopathy, with rescue experiments successfully preventing this phenotype in patient-derived heart tissues.
This study found that Nubian ibex have developed genetic adaptations in response to their desert environment, including enhanced skin barrier, DNA repair, viral response, and metabolism of toxic compounds.
May 2020 in “Research Square (Research Square)” This study used cashmere goats to reveal distinct intermediate states of dermal papilla cells, each with specific roles in hair growth, shedding, and regeneration.
January 2020 in “Medical journal of clinical trials & case studies” This report details a case of dystrophic epidermolysis bullosa in a 37-year-old male with a recessive mutation in the CLO7A1 gene, affecting type VII collagen.
April 2018 in “Journal of Investigative Dermatology” This study reports that in aged mice, hair follicle dermal stem cells exhibit diminished self-renewal and preferential differentiation into dermal sheath cells, contributing to age-related hair loss.
April 2018 in “Journal of Investigative Dermatology” This study found that both Th1 and Th2 cytokine markers were elevated in the serum and skin of patients with alopecia areata, with Th2 markers more closely linked to disease severity.
April 2018 in “Journal of Investigative Dermatology” This study found that activation of the transcription factor Nrf2 in keratinocytes promotes wound healing in mice by expanding hair follicle stem cells, independent of changes in keratinocyte proliferation or migration.
April 2018 in “Journal of Investigative Dermatology” In this study, topical tofacitinib significantly promoted hair regrowth in mice, outpacing both minoxidil and controls over 21 days, with findings suggesting increased VEGF levels and decreased inflammation as possible mechanisms.
October 2025 in “Cermin Dunia Kedokteran” This review discusses personalized treatment strategies and management approaches for chronic obstructive pulmonary disease (COPD), emphasizing the need for multi-aspect assessments, but reports no new clinical findings.
3 citations
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July 2021 in “Life science alliance” This study observed that disrupting the Pnkp gene in adult mice resulted in a premature aging-like phenotype, suggesting PNKP's vital role in maintaining normal growth and survival of certain progenitor cell populations.
April 2023 in “Journal of Investigative Dermatology” In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
November 2024 in “NeoReviews” Pallister-Killian Syndrome is a complex genetic disorder requiring coordinated care and genetic counseling.
June 2024 in “Deleted Journal” This review explored the potential of medicinal plants and natural compounds as alternative treatments for baldness, identifying several with anti-inflammatory and antioxidant properties that may help reduce hair loss.
May 2020 in “Business Innovation & Entrepreneurship Journal” This study discusses the development of a turmeric-based herbal hair removal product named PASIKULA, highlighting its potential to increase the economic value of turmeric and acceptance by consumers.
February 2026 in “HCA Healthcare Journal of Medicine” This review discusses identifying keratosis pilaris, its common mimics, and its associated skin diseases across different skin tones but reports no new results.
April 2026 in “Clinical Dermatology Review” In this study, patients with keratosis pilaris exhibited significant quality of life impairment, with histopathology and dermoscopy revealing consistent skin and hair changes.
July 2023 in “Media Dermato Venereologica Indonesiana” In this case report, a 60-year-old man with dermatosis pustular subkorneal showed improvement following treatment with systemic and topical corticosteroids over 4–5 weeks, as diagnosed through clinical and histopathological assessments.
June 2023 in “CHEDS Journal of Chemistry Education and Science” In this experimental study, researchers developed a hair tonic using green spinach leaves and assessed its feasibility based on vitamin content and sensory characteristics, finding that the tonic was generally liked by panelists in hedonic tests.
17 citations
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November 2000 in “Journal of Investigative Dermatology” ZPK helps skin cells mature and may affect skin health.
January 2026 in “Frontiers in Medicine” In this study, PP-PTKL exhibited antioxidant, anti-inflammatory, and pro-melanogenic effects in laboratory settings, suggesting its potential role in preventing or treating hair greying. Further animal and human studies are needed to verify these findings.
This study observed that a combination treatment of 2% topical minoxidil and oral vitamin D significantly improved hair density and vitamin D levels in women with female pattern hair loss, compared to minoxidil or vitamin D used alone.
June 2023 in “Journal of Biosciences and Health” This study found that all tested cats and 86.66% of dogs were carriers of dermatophytes like Microsporum canis, with cats showing higher prevalence, indicating these asymptomatic animals may significantly contribute to the spread of dermatophytosis and dermatomycoses.
20 citations
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November 2014 in “JAMA dermatology” This study found that three treatments with the 810-nm diode laser improved skin texture and roughness/bumpiness in keratosis pilaris patients, although it did not reduce redness.
February 2022 in “World Journal Of Advanced Research and Reviews” This study found that Peperomia pellucida plant extract may benefit hair growth, male libido, male fertility, and renal cell recovery.
99 citations
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February 2000 in “PubMed” This study found that overexpression of PKCepsilon in transgenic mice reduced papilloma development but accelerated carcinoma formation in a skin tumor promotion model.
87 citations
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September 2006 in “Clinical Cancer Research” This article reviews the diverse roles of protein kinase C (PKC) isozymes in cancer biology, highlighting their potential as therapeutic targets, but reports no new experimental results.