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The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.

Finasteride safely lowers DHT levels without affecting testosterone.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Finasteride effectively treats baldness but may cause sexual side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.