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The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

New treatments for male hypogonadism are effective and should be personalized.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

A diabetic cat with another gland issue got better after treatment with cabergoline, no longer needing insulin.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

People with reproductive, thyroid disorders, and type 2 diabetes can experience voice changes, but more research is needed to understand this better.

Ovulation disorders are a major cause of infertility and menstrual problems in women.

Dogs with sex hormone imbalances may not drink or pee a lot but often lose hair on their body and can have reproductive system issues.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.

Certain maturity signs appear before and after the first release of sperm in boys.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

A small number of premenopausal female blood donors had high prolactin levels, often due to stress, and retesting is recommended to prevent misdiagnosis.

Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.